A novel mutation in USF1 gene is associated with familial combined hyperlipidemia

ConclusionsWe speculate that this mutation [Arg196Trp] in theUSF1 gene might be associated with FCHL and early ‐onset coronary heart disease in this family. However, the substantial mechanism requires further investigation. These findings indicate thatUSF1 plays an important role in the biological pathways associated with lipid metabolism.

Source: IUBMB Life - November 13, 2019 Category: Research Authors: Eskandar Taghizadeh, Farzaneh Mirzaei, Nazanin Jalilian, Majid Ghayour Mobarhan, Gordon A. Ferns, Alireza Pasdar Tags: RESEARCH COMMUNICATION Source Type: research