3D printing helps unravel rare cardiac anomalies

A 3D-printed heart model based on patient MR images helped physicians identify...Read more on AuntMinnie.comRelated Reading: 3D printing may improve safety of upper GI surgery How can 3D printing improve kidney cancer surgery? 4D flow MRI, 3D printing improve congenital heart surgery 3D printing gives pediatric heart surgery a boost 3D printing bolsters care for congenital heart disease
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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ConclusionAlthough the investigated co-morbidities are capable or inducing pathophysiological changes that are predisposing factors for tumor progression, none is an independent prognostic factor in patients with RCC.
Source: World Journal of Urology - Category: Urology & Nephrology Source Type: research
Researchers from Australia have created a 3D-printed head model, based on a...Read more on AuntMinnie.comRelated Reading: How can 3D printing improve kidney cancer surgery? 3D printing enhances chest wall reconstruction 3D printing cuts hip fracture repair time, blood loss 3D printing bolsters surgery for multiple rib fractures 3D printing bolsters care for congenital heart disease
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
In this study, we determine whether transient reintroduction of embryonic stem cell cycle miR-294 promotes cardiomyocyte cell cycle reentry enhancing cardiac repair after myocardial injury. A doxycycline-inducible AAV9-miR-294 vector was delivered to mice for activating miR-294 in myocytes for 14 days continuously after myocardial infarction. miR-294-treated mice significantly improved left ventricular functions together with decreased infarct size and apoptosis 8 weeks after MI. Myocyte cell cycle reentry increased in miR-294 hearts parallel to increased small myocyte number in the heart. Isolated adult myocytes from miR-...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
This study provides a possible reason why genes carrying health risks have persisted in human populations. The second found evidence for multiple variants in genes related to ageing that exhibited antagonistic pleiotropic effects. They found higher risk allele frequencies with large effect sizes for late-onset diseases (relative to early-onset diseases) and an excess of variants with antagonistic effects expressed through early and late life diseases. There also exists other recent tangible evidence of antagonistic pleiotropy in specific human genes. The SPATA31 gene has been found under strong positive genomic sele...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusions: These findings are, to the best of our knowledge, the first cohort evidence relating solvent exposure levels among dry cleaners to elevated risks of selected cancers and heart disease. Additional studies employing solvent-specific exposure assessment are needed to clarify cancer risks associated with tetrachloroethylene.
Source: Epidemiology - Category: Epidemiology Tags: Cancer Source Type: research
CONCLUSIONS: A positive radiation dose response was observed for malignant and non-malignant kidney disease, and a negative dose response for malignant and non-malignant lung disease. Cumulative measures of dust were significantly associated with malignant and non-malignant lung disease and suggested for malignant and non-malignant kidney disease. Small numbers preclude definitive interpretations which will await the combination with similar studies of early uranium processing workers. PMID: 30652958 [PubMed - as supplied by publisher]
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research
ConclusionsThis systematic review supports existing recommendations for fruit and vegetable intakes. Current comparative risk assessments might significantly underestimate the protective associations of fruit and vegetable intakes.
Source: Journal of the Academy of Nutrition and Dietetics - Category: Nutrition Source Type: research
We report that the disruption of excitation-contraction coupling contributes to impaired force generation in the mouse model of Sod1 deficiency. Briefly, we found a significant reduction in sarcoplasmic reticulum Ca2+ ATPase (SERCA) activity as well as reduced expression of proteins involved in calcium release and force generation. Another potential factor involved in EC uncoupling in Sod1-/- mice is oxidative damage to proteins involved in the contractile response. In summary, this study provides strong support for the coupling between increased oxidative stress and disruption of cellular excitation contraction mac...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Abstract ObjectivesTo evaluate predictors of long‐term survival for patients with chronic kidney disease primarily due to surgery (CKD‐S). Patients with CKD‐S have generally good survival that approximates patients who do not have CKD even after renal cancer surgery (RCS), yet there may be heterogeneity within this cohort. Patients and MethodsFrom 1997‐2008, 4,246 patients underwent RCS at our center. Median follow‐up was 9.4 years (IQR=7.3‐11.0). New baseline GFR was defined as highest GFR between nadir and 6 weeks after surgery. We retrospectively evaluated 3 cohorts: no‐CKD (new baseline GFR≥60ml/min/1....
Source: BJU International - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research
Conclusion The results of this study provide further evidence for the link between increasing levels of fat and the risk of developing certain cancers. There was strong evidence for nine cancers, with another two – ovarian cancer and stomach cancer – included when comparing obesity with healthy weight. This study is important in showing the significance of fat levels and obesity in cancer risk. But there are some important things to consider: The study doesn't tell us how excess body fat might play a role in the development of certain cancers, just that there's a link. Some studies might have been missed,...
Source: NHS News Feed - Category: Consumer Health News Tags: Cancer Obesity Source Type: news
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