Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models
DiscussionDependent on animal model, both histopathological and biochemical end-points differed between sampling sites in the liver. Based on these findings, we recommend that sample site location is highly standardized and properly reported in order to minimize potential sampling variation and to optimize reproducibility and meaningful comparisons of preclinical studies of NAFLD.
Source: Journal of Pharmacological and Toxicological Methods - Category: Drugs & Pharmacology Source Type: research
More News: Alcoholism | Cholesterol | Diets | Drugs & Pharmacology | Fatty Liver Disease (FLD) | Guinea Health | High Fat | Liver | Liver Disease | Non-alcoholic Fatty Liver Diseases (NAFLD) | Nutrition | Statistics | Study | Toxicology | Urology & Nephrology