An overview of T follicular cells in transplantation: spotlight on their clinical significance.
We report on their relevance to alloimmunity and on the effects of immunosuppressive drugs on these immunocompetent cell populations.Expert opinion: Growing knowledge about the actions of Tfh and Tfr allows for a better understanding of the immunological mechanisms of ABMR after organ transplantation. This understanding feeds the hypothesis that immunosuppressive drugs targeting the actions of Tfh cells have huge therapeutic potential. This new concept in the treatment of the humoral rejection response will improve graft and patient survival after organ transplantation. PMID: 31721600 [PubMed - as supplied by publisher]
Biotechs race to serve patients stuck on waiting lists for organs
Long-term data show better overall survival after an allogeneic transplant for relapsed follicular lymphoma than with autologous transplant, but an expert wonders about recommending transplant at all.Medscape Medical News
Autologous hematopoietic stem cell transplants have increased globally, but predominantly in high income nations, and there are marked disparities in usage.Medscape Medical News
ConclusionsThe factors associated positively with DKT were duration after surgery, improvement of physical activities, mobility, alleviation of pain, and patient satisfaction.
Dylan Mortimer creates celestial and glittery interpretations of scars, lungs and operating rooms.
This article reviews some epidemiological, clinical, diagnostic and therapeutic aspects of these conditions. PMID: 31803301 [PubMed]
"Age has no implication in terms of the antimyeloma effect of transplant," said one oncologist. Researchers called this largest study of auto-HCT in older adults with multiple myeloma.Medscape Medical News
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
A BRAVE three-year-old boy on the transplant register has asked Santa for a new heart, as the NHS launches an appeal for child organ donors this Christmas.
Authors: Anqi C, Takabatake K, Kawai H, Oo MW, Yoshida S, Fujii M, Omori H, Sukegawa S, Nakano K, Tsujigiwa H, Jinhua Z, Nagatsuka H Abstract The stroma affects the properties and dynamics of the tumor. Previous studies have demonstrated that bone marrow-derived cells (BMDCs) possess the capability of differentiating into stromal cells. However, the characteristics and roles of BMDCs in oral squamous cell carcinoma remain unclear. The current study therefore investigated their locations and features by tracing green fluorescent protein (GFP)-labeled BMDCs in a transplantation mouse model. After irradiation, BALB-c ...