Vessel Wall Imaging of Cerebrovascular Disorders
AbstractPurpose of reviewHigh-resolution magnetic resonance vessel wall imaging (VWI) permits direct visualization of intracranial arterial wall pathology, providing diagnostic and prognostic information that is complementary to conventional imaging techniques. We highlight the most recent studies that have advanced the clinical application of VWI.Recent findingsVWI aids in distinguishing and diagnosing intracranial atherosclerotic disease (ICAD), intracranial dissections, central nervous system vasculitis, reversible cerebral vasoconstriction syndrome, and moyamoya disease. VWI may help predict recurrent stroke in ICAD, treatment effects in vasculitis, and disease progression in moyamoya. VWI also identifies ruptured intracranial aneurysms and may predict stability of unruptured aneurysms.SummaryImplementing VWI as an adjunctive imaging technique may permit earlier and noninvasive discrimination of rare vasculopathies. However the prognostic utility of VWI for more common cerebrovascular pathologies requires further validation.
Authors: Shimamura Y, Ogawa Y, Shinohara T PMID: 32067820 [PubMed - as supplied by publisher]
ConclusionHistory of hearing amplification and current amplification predict cochlear implant qualification. Hearing aids fitted at the time of cochlear implantation evaluation may result in lower qualification rates.
ConclusionsThe present study demonstrates that IPEE treatments can enhance cerebral ischemic tolerance by regulating the toll-like receptor 4 (TLR4) signaling pathway. The mechanisms of this response come in two primary forms: inhibiting MyD88 dependent pro-inflammatory pathways and activating TRIF dependent anti-inflammatory pathways.Graphical abstract
Publication date: Available online 19 February 2020Source: Canadian Journal of CardiologyAuthor(s): Hsin-Fu Lee, Yi-Hsin Chan, Pei-Ru Li, Jia-Rou Liu, Tze-Fan Chao, Lung-Sheng Wu, Shang-Hung Chang, Yung-Hsin Yeh, Chi-Tai Kuo, Lai-Chu See, Gregory Y.H. LipAbstractBackgroundEvidences of clinical outcomes for oral anticoagulants and antiplatelet treatment (APT) in atrial fibrillation (AF) patients with critical limb ischemia (CLI) are very limited.MethodsIn this nationwide retrospective cohort study collected from Taiwan National Health Insurance Research Database, 1,223 AF patients with CLI taking DOACs, warfarin, or APT wer...
ConclusionIn the presented report, in patients with nonvalvular atrial fibrillation the LAmbre offered similar long ‐term efficacy and safety in comparison to Amplatzer devices.This article is protected by copyright. All rights reserved.
We examined the current studies on the efficiency and effectiveness of the robot interventions and produced a taxonomy of the review. An original finding of the current robotics in rehabilitation landscaping are critical presented with recommendations and concluding remarks concerning interdisciplinary impact. PMID: 32067201 [PubMed - in process]
AbstractA child with vertical transmission of human immunodeficiency virus refractory to therapy developed zoster-induced protein S deficiency and recurrent strokes. Extensive carotid arteritis was found postmortem. The carotid tissue was positive for herpes varicella zoster by polymerase chain reaction, as were immunofixation stains of the arterial wall.
Neurological involvement in human immunodeficiency virus (HIV) type 1 infection are frequent and include: peripheral neuropathy, central nervous system infections, neoplasms, stroke and myopathies . Prevalence of muscle disease in HIV infection is low, found in less than 1% of patients with AIDS, and myopathy may occur at any stage of immunosuppression. Many neuromuscular disorders are described in HIV infected patients: polymyositis, myopathy induced by nucleoside reverse transcriptase inhibitors (NRTI) such as zidovudine, muscle opportunistic infections of skeletal muscle tissue, such as toxoplasmosis, HIV associated ...
Conclusions: Prevalence of CVS risk factors was significant in our population. Stroke in HIV patients may result from other disease mechanisms and carries significant mortality and morbidity. Fever at presentation suggests an infective etiology.Disclosure: Dr. Gan holds stock and/or stock options in a company which sponsored research in which Dr. Gan was involved as an investigator. Dr. Saini has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Ng has nothing to disclose. Dr. Tan has nothing to disclose.
Conclusions: There was a high frequency of cerebral arterial disease in this neuroimaging cohort of HIV/AIDS patients. A history of cART use and a history of tobacco abuse were independent risk factors for vasculopathy, though these findings should be confirmed with large-scale prospective studies.Cerebrovasc Dis 2016;41:170-176