Meth-Related HF Worse, Responds Well to Meds if Abuse Stops Meth-Related HF Worse, Responds Well to Meds if Abuse Stops
Patients with heart failure from methamphetamine abuse tend to be worse off than others with HF, clinically and by echocardiography. But meds work just as well if the meth abuse stops, a study suggests.Medscape Medical News
Publication date: November–December 2020Source: Heart &Lung, Volume 49, Issue 6Author(s): Linda Clements, Susan K. Frazier, Debra K. Moser, Terry A. Lennie, Misook L. Chung
CONCLUSIONS: Elevated plasma TMAO level in patients with heart failure is associated with poorer prognoses. This association is only partially mediated by renal dysfunction. PMID: 32959366 [PubMed - as supplied by publisher]
Authors: Hughes TF, Liu A, Jacobsen E, Rosano C, Berman SB, Chang CH, Ganguli M Abstract INTRODUCTION: Although exercise is associated with a lower risk for mild cognitive impairment (MCI), it is unclear whether its protective effect depends on the presence or absence of vascular factors. METHODS: In an exploratory study of data from a population-based cohort, 1254 participants aged 65+ years were followed for 10 years for incident MCI. The main effect of baseline total minutes of exercise per week (0 vs. 1 to 149 vs. 150+), and its interaction with several vascular factors, on risk for incident MCI was examine...
CONCLUSIONS: The CADOT index has comparable prognostic power to the BODE and ADO indices. The CADOT is complementary/an alternative to the BODE (if 6-MWT is not feasible) and ADO (with less dependence on the age factor) indices. TRIAL REGISTRATION: ClinicalTrials.gov (NCT01923051). PMID: 32955038 [PubMed - as supplied by publisher]
Publication date: Available online 23 September 2020Source: Revista Española de Cardiología (English Edition)Author(s): Julio Núñez, Héctor Merenciano-González, Enrique Santas, María Pilar López-Lereu, José Vicente Monmeneu, Ernesto Valero
Dr Akshay Desai, of Harvard Medical School, reviews key studies on heart failure, presented at the European Society of Cardiology (ESC) Congress 2020, which was held as a virtual conference.Medscape
Remote optimization of drugs for heart failure patients with reduced ejection fraction could support implementation of guideline-directed medical therapy, researchers say.Reuters Health Information
Authors: Majos-Karwacka E, Kraska A, Kowalik I, Smolis-Bak E, Lipiec P, Kasprzak J, Szwed H, Dabrowski R Abstract BACKGROUND: The right ventricle (RV) function is crucial in heart failure with reduced ejection fraction (HFrEF), especially in patients with atrial fibrillation (AF). Aims. To assess the RV structure and function in patients with HFrEF, permanent atrial fibrillation (AF), cardiac resynchronization therapy (CRT) and RV pacing (RVp) with two- and three-dimensional echocardiography. Methods. Patients with ischemic HFrEF (NYHA II-III; LVEF ≤40%) were enrolled. The studied groups were: sinus rhythm (SR, ...
Conclusions: Both center-dependent clinical practice standards and patient clinical conditions substantially contributed to the risk of lowQsub. We confirmed previous evidence indicating better survival among patients withQsub≥ 21 L/session.Blood Purif
Authors: Yi C, Si L, Xu J, Yang J, Wang Q, Wang X Abstract Myocardial ischemia-reperfusion injury (MIRI) is a major cause of heart failure in patients with coronary heart disease. The excessive accumulation of reactive oxygen species (ROS) during MIRI induces the overactivation of an autophagic response, which aggravates myocardial cell damage. Asiatic acid (AA) is a triterpenoid compound, which is extracted from Centella asiatica and exhibits a variety of pharmacological effects such as hepatoprotective, neuroprotective and antioxidant. However, the association of AA with autophagy in MIRI is not fully understood....