The clinical value of detecting microcalcifications on a mammogram

Publication date: Available online 14 November 2019Source: Seminars in Cancer BiologyAuthor(s): Tibor Tot, Maria Gere, Syster Hofmeyer, Annette Bauer, Ulrika PellasAbstractMany breast lesions are associated with microcalcifications that are detectable by mammography. In most cases, radiologists are able to distinguish calcifications usually associated with benign diseases from those associated with malignancy. In addition to their value in the early detection of breast carcinoma and accurate radiological diagnosis, the presence of microcalcifications often affects the extent of surgical intervention. Certain types of microcalcifications are associated with negative genetic and molecular characteristics of the tumor and unfavorable prognosis. Microcalcifications localized in the larger ducts (duct-centric, casting-type microcalcifications) represent an independent negative prognostic marker compared to lesions containing other types of microcalcifications and to non-calcified lesions. In this review, we summarize the theoretical and methodological background for understanding the clinical impact and discuss the diagnostic and prognostic value of microcalcifications detected in the breast by mammography.
Source: Seminars in Cancer Biology - Category: Cancer & Oncology Source Type: research

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Source: Cancer Causes and Control - Category: Cancer & Oncology Source Type: research
While there has been some controversy over when women should start getting mammograms, all experts agree that screening is an important first step in detecting breast cancers and treating them early. But for some women, that’s not enough. For the approximately 40% of women with dense breast tissue, and especially the 10% with extremely dense tissue, cancer cells are harder to detect, since the denser tissue can mask small growths. In addition, dense breast tissue itself is also a risk factor for developing cancer. There’s been debate among experts over whether these women should have additional screening, on to...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Breast Cancer embargoed study Research Source Type: news
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Source: La Radiologia Medica - Category: Radiology Source Type: research
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Source: European Journal of Radiology - Category: Radiology Source Type: research
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Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Original Research Source Type: research
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Source: Journal of Computer Assisted Tomography - Category: Radiology Tags: Breast Imaging Source Type: research
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Source: Yonsei Medical Journal - Category: Universities & Medical Training Authors: Tags: Yonsei Med J Source Type: research
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Source: European Journal of Radiology - Category: Radiology Source Type: research
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Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
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