Electrochemical detection of serotonin: A new approach.

Electrochemical detection of serotonin: A new approach.
Clin Chim Acta. 2019 Nov 09;:
Authors: Khoshnevisan K, Honarvarfard E, Torabi F, Maleki H, Baharifar H, Faridbod F, Larijani B, Reza Khorramizadeh M
Abstract
Serotonin (5-hydroxytryptamine, 5-HT) is an important neurotransmitter which plays a significant role in various functions in the body, such as appetite, emotions, and autonomic functions. It is well known that biomarker 5-HT levels can be correlated to several diseases and disorders such as depression, anxiety, irritable bowel, and sleep trouble. Among various methods for detecting the 5-HT biomarker, electrochemical techniques have attracted great interest due to their low cost and ease of operation. However, sensitive and precise electrochemical detection of 5-HT levels is not possible using bare electrodes, thus requiring electrode modification. The present review aims to describe the different electroanalytical methods for 5-HT detection using various surface-modified electrodes such as glassy carbon, carbon fiber, diamond, graphite, and metal electrodes modified with conductive polymers. Perspectives and the modification of electrode surface using applied polymers for 5-HT detection have also been presented.
PMID: 31715139 [PubMed - as supplied by publisher]

Source: International Journal of Clinical Chemistry - November 8, 2019 Category: Chemistry Authors: Khoshnevisan K, Honarvarfard E, Torabi F, Maleki H, Baharifar H, Faridbod F, Larijani B, Reza Khorramizadeh M Tags: Clin Chim Acta Source Type: research