Metals in biotechnology: Cr-driven-stereoselective reduction of conjugated C=C-double bonds.

Metals in biotechnology: Cr-driven-stereoselective reduction of conjugated C=C-double bonds. Chembiochem. 2019 Nov 12;: Authors: Rauch M, Gallou Y, Delorme L, Paul C, Arends I, Hollmann F Abstract Elementary metals are shown to be suitable sacrificial electron donors to drive stereoselective reduction of conjugated C=C-double bonds using old yellow enzymes as catalysts. Both, direct electron transfer from the metal to the enzyme as well as mediated electron transfer is feasible, though the latter excels by higher reaction rates. The general applicability of this new chemoenzymatic reduction method is demonstrated as well as current limitations are outlined. PMID: 31713969 [PubMed - as supplied by publisher]
Source: Chembiochem - Category: Biochemistry Authors: Tags: Chembiochem Source Type: research