Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease

Nature, Published online: 13 November 2019; doi:10.1038/s41586-019-1742-xIn patients with alcoholic hepatitis, cytolysin-positive Enterococcus faecalis strains are correlated with liver disease severity and increased mortality, and in mouse models these strains can be specifically targeted by bacteriophages.

Source: Nature AOP - November 12, 2019 Category: Research Authors: Yi Duan Cristina Llorente Sonja Lang Katharina Brandl Huikuan Chu Lu Jiang Richard C. White Thomas H. Clarke Kevin Nguyen Manolito Torralba Yan Shao Jinyuan Liu Adriana Hernandez-Morales Lauren Lessor Imran R. Rahman Yukiko Miyamoto Melissa Ly Bei Gao Wei Source Type: research