Adherence to the pro-inflammatory diet in relation to prevalence of irritable bowel syndrome

We examined the association between DII score and odds ...
Source: Nutrition Journal - Category: Nutrition Authors: Tags: Research Source Type: research

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AbstractMinesapride (drug code: DSP ‐6952) is a potential gastrointestinal prokinetic agent with high selectivity for 5‐hydroxytryptamine 4 (5‐HT4) receptor that acts as a partial agonist. Although 5 ‐HT4 receptor agonists are expected to show efficacy in patients with irritable bowel syndrome with constipation, only tegaserod is available for female patients, with limitations, in the United States. Previously, another 5 ‐HT4 receptor agonist, cisapride, was widely used for the treatment of upper gastrointestinal diseases, but was withdrawn from the market because of arrhythmia with QT prolongation. Chemically, b...
Source: Clinical Pharmacology in Drug Development - Category: Drugs & Pharmacology Authors: Tags: Original Manuscript Source Type: research
Nature Reviews Gastroenterology &Hepatology, Published online: 27 February 2020; doi:10.1038/s41575-020-0282-zFaecal microbiota transplantation (FMT) aims to restore an altered microbiota and has been suggested as a potential treatment option for irritable bowel syndrome (IBS), among other diseases. A new study suggests that the use of a so-called superdonor is necessary to successfully treat patients with IBS using FMT.
Source: Nature Reviews Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
Publication date: Available online 25 February 2020Source: Neuroscience LettersAuthor(s): Jie Li, Binke Yuan, Guoxiong Li, Xingqi Lu, Yun Guo, Ying Yang, Minjie Liang, Jianping Ding, Quan Zhou
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Authors: Mazzawi T, Eikrem Ø, Lied GA, Hausken T Abstract Altered densities of enteroendocrine cells play an important role in patients with irritable bowel syndrome (IBS). Uroguanylin activates guanylate cyclase-C to regulate intestinal electrolyte and water transport. Aim. To quantify uroguanylin immunoreactive cells density in the duodenum of diarrhea-predominant IBS (IBS-D) patients compared to controls and to investigate the effect of fecal microbiota transplantation (FMT) on these cell densities. Method. Twelve patients with IBS-D according to Rome III criteria were included. The cause was identified a...
Source: Gastroenterology Research and Practice - Category: Gastroenterology Tags: Gastroenterol Res Pract Source Type: research
Condition:   Irritable Bowel Syndrome Interventions:   Dietary Supplement: Fructans;   Dietary Supplement: Glucose;   Dietary Supplement: Saline Sponsor:   Universitaire Ziekenhuizen Leuven Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Uterine fibroids affect up to 80% of reproductive-aged women. Although many women are asymptomatic, fibroids can cause pelvic pain, abnormal uterine bleeding, anemia, urinary frequency, infertility, and adverse pregnancy outcomes that can impair quality of life. Fifty percent of women with symptomatic fibroids report a detrimental impact on their mental and physical health (1). Fibroids appear to have a greater impact on quality of life than other chronic conditions, including asthma, irritable bowel syndrome, and gastroesophageal reflux disease (2).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
By David Tuller, DrPH I have been trying to find out why Mahana Therapeutics, a San Francisco-based start-up, has chosen to disseminate misleading information about a web-based cognitive behavior therapy program for people with irritable bowel syndrome. Because Mahana’s co-founder and CEO, Rob Paull, has not responded to my letters, I have contacted some of […]
Source: virology blog - Category: Virology Authors: Tags: Uncategorized Source Type: blogs
CONCLUSIONS: We found DEGs and DEMs in FM patients through bioinformatics analysis, which may be involved in the occurrence and development of FM and serve as potential targets for diagnosis and treatment. PMID: 32083545 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Irritable bowel syndrome (IBS) has been gradually recognized as a disorder of the brain-gut interaction, but the molecular changes in the brain and colon that occur in disease development remain poorly underst...
Source: Proteome Science - Category: Bioinformatics Authors: Tags: Research Source Type: research
A 58-year-old female presents with a 1-year history of hematochezia, 20-pound weight loss, and increased straining with bowel movements. She denies increased bowel frequency or change in stool caliber. Her medical history is notable for irritable bowel syndrome, but otherwise unremarkable. She has no family history of malignancy and does not take any prescribed medications or supplements. She denies abdominal pain, bone pain, or any symptoms concerning for metastatic disease. Her initial physical examination was notable for an Eastern Cooperative Oncology Group performance status of 0, and presence on digital rectal examin...
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research
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