Deadly superbugs pose greater threat than previously estimated

Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news

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In conclusion, after digestion the AR traits of antibiotic-resistant (also VBNC) enterococci contained in seafood may be maintained and transferred to the human microbiota and from it to intestinal pathogens.
Source: Food Control - Category: Food Science Source Type: research
Authors: Boia S, Boariu M, Baderca F, Rusu D, Muntean D, Horhat F, Boia ER, Borza C, Anghel A, Stratul ŞI Abstract Aim of research was to evaluate and compare the clinical and microbiological effects of two different regimens of amoxicillin (AMX) and metronidazole (MTZ) combined with non-surgical periodontal therapy in patients with chronic periodontitis (CP), and identify antibiotic-resistant bacteria and changes in oxidative stress (OS). Forty-six patients with generalized CP were randomly assigned to group A [scaling and root planing within 24 h (SRP) + placebo for 7 days), group B [SRP + AMX + MTZ, both 500 mg...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
There's been an uptick in the number of laboratory studies showing how just one mutation could create highly infectious or "hypervirulent" strains of disease-causing bacteria, fungi and water molds.
Source: WebMD Health - Category: Consumer Health News Source Type: news
Publication date: Available online 10 December 2019Source: Progress in Natural Science: Materials InternationalAuthor(s): Kaifeng Chen, Shan Jiang, Yun Hong, Zibiao Li, Yun-Long Wu, Caisheng WuAbstractCRISPR/Cas9 (clustered regularly interspaced short palindromic repeat/clustered regularly interspaced short palindromic repeat associated proteins 9) gene editing platform is a promising therapeutic tool for genetic disorders, due to its ability to manipulate the pathogenic gene in genomic level and to easily target specific gene by manipulating single-guide RNA. However, its successful delivery remains a challenge. Up to now...
Source: Progress in Natural Science: Materials International - Category: Materials Science Source Type: research
TUESDAY, Dec. 10, 2019 -- Makeup is a daily staple for most women, but new research finds that 9 of 10 beauty products may harbor superbugs after they're opened. Beauty blenders (sponges used to apply foundation or other products to the face),...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
CONCLUSION: Our data showed the potential of this series for exploring new and more effective antibacterial in order to develop in vivo and against other resistant bacteria. PMID: 31820692 [PubMed - as supplied by publisher]
Source: Current Topics in Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Top Med Chem Source Type: research
AbstractThe aim of this study was to evaluate the diagnostic accuracy and the clinical impact of isothermal loop-mediated amplification (LAMP; eazyplex ® MRSA kits) for rapid diagnosis ofStaphylococcus aureus bacteremia (SAB) in comparison with conventional blood culture diagnostics. We performed a retrospective, single-center observational study over the period between November 2016 and December 2018 on patients (and blood cultures) with growth of Gram-positive cocci in clusters in their blood cultures. We quantified diagnostic accuracy with sensitivity and specificity for detection ofS. aureus, methicillin-resistantS...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research
Over the past few decades, antimicrobial resistance has emerged as an important threat to public health due to the global dissemination of multidrug-resistant strains from several bacterial species. This worrisome trend, in addition to the paucity of new antibiotics with novel mechanisms of action in the development pipeline, warrants the development of non-antimicrobial approaches to combating infection caused by these isolates. Monoclonal antibodies (mAbs) have emerged as highly effective molecules for the treatment of multiple diseases. However, in spite of the fact that antibodies play an important role in protective i...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewIn the last year, an increasing number of studies have reported on methicillin-resistantStaphylococcus aureus (MRSA) transmission in Africa and Asia and in migrant workers. We reviewed original research on occupational health and safety of animal workers published from January 1, 2018, through June 30, 2019, with a targeted focus on infectious disease studies published in these populations.Recent FindingsStudies focused on occupational exposures to infectious agents, dust and allergens, pesticides, and occupational injury. Research on zoonotic MRSA used whole genome –sequencing technologies t...
Source: Current Environmental Health Reports - Category: Environmental Health Source Type: research
The Centers for Disease Control and Prevention (CDC) has recently identified medical devices used in the ICU as a major source of antibiotic-resistant infections. N8 Medical’s CeraShield technology may help reduce such infections by preventing fouling and formation of bacterial and fungal biofilms on device surfaces. FDA has designated the company’s CeraShield Endotracheal Tube (ETT) as a “breakthrough” device, pursuant to the 21st Century Cures Act based on its potential life-saving properties. And N8 reported that ...
Source: MDDI - Category: Medical Devices Authors: Tags: Materials Source Type: news
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