Medical News Today: What to know about hair loss and Accutane

Accutane, a drug that helps treat severe acne, contains isotretinoin. Isotretinoin may cause side effects, including hair loss. Learn more about why Accutane may cause hair loss, and some ways to counter it, here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Dermatology Source Type: news

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Background: Eccrine duct dilation (EDD) was recently described to occur more frequently in cicatricial alopecias than noncicatricial alopecias. Because single EDD can be useful in the evaluation of alopecias, we aimed to determine whether dilation of multiple eccrine duct units, or “multiple eccrine duct dilation (MEDD),” could more specifically discriminate between cicatricial and noncicatricial alopecias. Methods: We retrospectively evaluated 611 scalp biopsies (342 cicatricial alopecias and 269 noncicatricial alopecias). Results: Among cicatricial alopecias, MEDD was found in 21% (25/118) of central ...
Source: The American Journal of Dermatopathology - Category: Pathology Tags: CME Article Source Type: research
The increasing prevalence of Metabolic syndrome (MetS) is a worldwide health problem, and the association between MetS and skin diseases has recently attracted growing attention. In this review, we summarize the associations between MetS and skin diseases, such as psoriasis, acne vulgaris, hidradenitis suppurativa, androgenetic alopecia, acanthosis nigricans, and atopic dermatitis. To discuss the potential common mechanisms underlying MetS and skin diseases, we focus on insulin signaling and insulin resistance, as well as chronic inflammation including adipokines and proinflammatory cytokines related to molecular mechanism...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Publication date: Available online 13 November 2019Source: Clinica Chimica ActaAuthor(s): Xin Zeng, Yuan-jie Xie, Ya-ting Liu, Shuang-lian Long, Zhong-cheng MoAbstractPolycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic abnormalities, including insulin resistance, excessive weight or obesity, type II diabetes, dyslipidemia and an increased risk of cardiovascular disease. The most significant clinical manifestation of PCOS is hyperandrogenism. Excess androgen profoundly affects granulosa cell function and...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Abstract Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease characterized by clinical or laboratorial hyperandrogenism, oligo-anovulation and metabolic abnormalities, including insulin resistance, excessive weight or obesity, type II diabetes, dyslipidemia and an increased risk of cardiovascular disease. The most significant clinical manifestation of PCOS is hyperandrogenism. Excess androgen profoundly affects granulosa cell function and follicular development via complex mechanisms that lead to obesity and insulin resistance. Most PCOS patients with hyperandrogenism have steroid sec...
Source: International Journal of Clinical Chemistry - Category: Chemistry Authors: Tags: Clin Chim Acta Source Type: research
ConclusionsSeven new signals that were not included in the current label were identified for TNF α inhibitors and should be updated and monitored.Key Points•Large-scale spontaneous AE reporting data and data mining techniques are useful for detecting signals of rare AEs as well as common AEs induced by drugs.•Drug labels should be updated to reflect signals that are newly discovered by continuous monitoring.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
This article highlights the clinical presentations of these conditions in skin of color and briefly addresses pathophysiology and treatment modalities.
Source: Journal of Pediatric Health Care - Category: Pediatrics Authors: Tags: Pharmacology Continuing Education Source Type: research
Authors: Piraccini BM, Berardesca E, Fabbrocini G, Micali G, Tosti A Abstract One of the most common micronutrient deficiencies with cutaneous findings is the vitamin B, also known as biotin, deficiency. Biotin deficiency may be due to congenital lack of biotinidase, or acquired following some conditions that interfere with its absorption, such as inflammatory bowel disorders, a diet too rich in avidin, magnesium deficiency, smoking habit and treatment with broad-spectrum antibiotics, anticonvulsants and sulfonamides. This review highlights the role of biotin in the most common skin disorders such associated with b...
Source: Giornale Italiano di Dermatologia e Venereologia - Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research
“I’m not a teenager anymore, why do I still have acne?!” This is a question we hear from patients on a daily basis. The truth is, it is quite common to see acne persist into adulthood. Although acne is commonly thought of as a problem of adolescence, it can occur in people of all ages. Adult acne has many similarities to adolescent acne with regard to both causes and treatments. But there are some unique qualities to adult acne as well. What causes adult acne? Adult acne, or post-adolescent acne, is acne that occurs after age 25. For the most part, the same factors that cause acne in adolescents are at pl...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Skin and Hair Care Source Type: blogs
Introduction: Polycystic ovary syndrome (PCOS) is an idiopathic endocrine disorder that commonly presents with cutaneous signs of hyperandrogenism, including acne, hirsutism, and androgenic alopecia. Current literature on patient demographics that predict successful management of acne in PCOS is limited. The aim of this study is to assess the role of patient demographics and medications in PCOS acne management.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Case Report: A 67-year-old woman with a history of rosacea presented with recalcitrant cystic acne. Additionally, the patient reported a 2-year history of gradual scalp hair loss and an increase in facial hair. There was no personal or family history of alopecia, hirsutism, or hyperandrogenism. Physical examination revealed excessive hair on her upper lip, chin, and lateral cheeks. She also had severe frontoparietal hair loss, thinning on the crown, and nodulocystic acne on her chin and cheeks. Laboratory tests showed markedly elevated levels of total testosterone (539 ng/dL), free testosterone (61.8 pg/mL) and DHEA-S (258 ug/dL).
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
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