Positive oligoclonal bands and CSF pleocytosis in narcolepsy type 1: A case report supporting the immune-mediated hypothesis

We report the case of a 16  year-old girl with excessive daytime sleepiness, hypnagogic/hypnopompic hallucinations and cataplexy, fulfilling narcolepsy-type 1 diagnostic criteria. She was HLA-DQB1*06:02/DQA1*01:02 positive. CSF analysis demonstrated positive IgG oligoclonal bands, pleocytosis and hypocretin-1 below detectio n limit.

Source: Journal of Neuroimmunology - November 12, 2019 Category: Allergy & Immunology Authors: Ana Moreno-Est ébanez, Iker Bilbao Villabeitia, Teresa Echeverria Guibert, Mar Mendibe Bilbao, Sabas Boyero Durán, Laura Cabral Martínez, Tirso González-Pinto, Garazi Agirre Beitia, Amaia González Eizaguirre, Alfredo Rodríguez-Antigüedad Tags: Short Communication Source Type: research