Exercise as Medicine in Multiple Sclerosis —Time for a Paradigm Shift: Preventive, Symptomatic, and Disease-Modifying Aspects and Perspectives

AbstractPurpose of ReviewFor many years, exercise was controversial in multiple sclerosis (MS) and thought to exacerbate symptoms and fatigue. However, having been found to be safe and effective, exercise has become a cornerstone of MS rehabilitation and may have even more fundamental benefits in MS, with the potential to change clinical practice again. The aim of this review is to summarize the existing knowledge of the effects of exercise as primary, secondary, and tertiary prevention in MS.Recent FindingsInitial studies established exercise as an effective symptomatic treatment (i.e., tertiary prevention), but recent studies have evaluated the disease-modifying effects (i.e., secondary prevention) of exercise as well as the impact on the risk of developing MS (i.e., primary prevention).SummaryBased on recent evidence, a new paradigm shift is proposed, in which exercise at an early stage should be individually prescribed and tailored as “medicine” to persons with MS, alongside conventional medical treatment.
Source: Current Neurology and Neuroscience Reports - Category: Neuroscience Source Type: research

Related Links:

Publication date: Available online 30 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): R.D. Russell, L.J. Black, N.M. Pham, A. Begley
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: August 2020Source: Multiple Sclerosis and Related Disorders, Volume 43Author(s): Amgad Droby, Lazar Fleysher, Maria Petracca, Kornelius Podranski, Junqian Xu, Michelle Fabian, Malgorzata Marjańska, Matilde Inglese
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Publication date: Available online 29 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Helena Beatriz Ferreira, Bruna Neves, Inês M. Guerra, Ana Moreira, Tânia Melo, Artur Paiva, M. Rosário Domingues
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
CONCLUSION: On the basis of a broadly based research and participatory development process, a set of indicators has been developed that enables comprehensive evaluation of the regional quality of care of cross-indication, integrated care models focusing on common diseases. In order to be able to increasingly evaluate aspects of care coordination and patient orientation, health promotion as well as nursing, palliative and emergency care in the future, it would be helpful if routine data were collected or made accessible in these areas as well. PMID: 32467041 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - Category: Health Management Tags: Z Evid Fortbild Qual Gesundhwes Source Type: research
TRIUMPHANT, a new placebo-controlled trial, has not shown any benefit over placebo of three different drugs commonly used to treat fatigue in patients with multiple sclerosis.Medscape Medical News
Source: Medscape Psychiatry Headlines - Category: Psychiatry Tags: Neurology & Neurosurgery News Source Type: news
Conditions:   Multiple Sclerosis;   Menstrual Pain;   Anxiety;   Fatigue;   Neurologic Symptoms Interventions:   Other: pain;   Other: fatigue;   Other: anxiety;   Other: position sense;   Other: balance;   Other: dual task performance Sponsor:   Ankara Yildirim Beyazıt University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Multiple Sclerosis;   Traumatic Brain Injury Interventions:   Behavioral: Emotional Processing Training;   Behavioral: Placebo Control Sponsor:   Kessler Foundation Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Multiple Sclerosis;   Menstrual Pain;   Anxiety;   Fatigue;   Neurologic Symptoms Interventions:   Other: pain;   Other: fatigue;   Other: anxiety;   Other: position sense;   Other: balance;   Other: dual task performance Sponsor:   Ankara Yildirim Beyazıt University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 28 May 2020Source: Multiple Sclerosis and Related DisordersAuthor(s): Konstantin Balashov, Suhayl Dhib-Jalbut, Igor Rybinnik
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
FRIDAY, May 29, 2020 -- Air pollution may be an environmental risk factor for multiple sclerosis, according to a study presented May 22 at the European Academy of Neurology Virtual Congress. Roberto Bergamaschi, M.D., Ph.D., from the IRCCS Mondino...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
More News: Brain | Multiple Sclerosis | Neurology | Neuroscience | Rehabilitation | Sports Medicine | Study