Microsatellite Instability Status is Determined by Targeted Sequencing with MSIcall in 25 Cancer Types

ConclusionWe demonstrated newly developed MSI-NGS with MSIcall accurately determines the MSI status of FFPE tumor tissues thorough sequencing of tumor samples alone without patient-matched normal controls. This approach could be applied to all types of solid tumors to determine responders to immune-oncology therapy.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research