Holistic, Patient-centred Approach Needed To Tackle Obesity Holistic, Patient-centred Approach Needed To Tackle Obesity

The individual's needs and goals should be a central part of obesity management, says UK expert, with a skilled multidisciplinary team helping to pick the right treatment for the right patient.Medscape News UK
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

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Macrophages are heterogeneous leukocytes regulated in a tissue- and disease-specific context. While in vitro macrophage models have been used to study diseases empirically, a systematic analysis of the transcriptome thereof is lacking. Here, we acquired gene expression data from eight commonly-used in vitro macrophage models to perform a meta-analysis. Specifically, we obtained gene expression data from unstimulated macrophages (M0) and macrophages stimulated with lipopolysaccharides (LPS) for 2–4 h (M-LPSearly), LPS for 24 h (M-LPSlate), LPS and interferon-γ (M-LPS+IFNγ), IFNγ (M-IFNγ), inter...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
For every one point lower BMI, people are at 1.37-fold lower risks for developing type 2 diabetes - even if they are not overweight or obese, new Stanford University research suggests.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
A study found that a 1 kg/m squared reduction in BMI in non-overweight individuals reduced reduced their risk for developing type II diabetes by as much as 37 percent.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
by Michael Wainberg, Anubha Mahajan, Anshul Kundaje, Mark I. McCarthy, Erik Ingelsson, Nasa Sinnott-Armstrong, Manuel A. Rivas BackgroundLifestyle interventions to reduce body mass index (BMI) are critical public health strategies for type 2 diabetes prevention. While weight loss interventions have shown demonstrable benefit for high-risk and prediabetic individuals, we aimed to determine whether the same benefits apply to those at lower risk. Methods and findingsWe performed a multi-stratum Mendelian randomization study of the effect size of BMI on diabetes odds in 287,394 unrelated individuals of self-reported white Brit...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
ConclusionsPost-prandial plasma metabolomics profiles suggest that a 2-m-long BLP RYGB does not have a negative impact on acute metabolite absorption. RYGB BPL length seems to influence post-prandial acetate levels, which could contribute to the additional positive metabolic outcomes.
Source: Obesity Surgery - Category: Surgery Source Type: research
In this study, we hypothesize that the choline and geranate (CAGE) ionic liquid can reduce...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biological Sciences Source Type: research
Overweight patients have largely negative interactions with physicians about their weight, even though these interactions are few and far between.Medscape Medical News
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
This study raises serious concerns about whether we’ve been careful enough about the safety of this chemical,” said Patricia Hunt, a professor of molecular bioscience at Washington State, and a corresponding author of the paper, in a statement. Despite how huge the difference, the results are not getting much evident pushback from other researchers in the field. “It honestly blew my mind—not because I don’t believe it, but because it appears to be true,” says Lori Hoepner, assistant professor of environmental and occupational health sciences at SUNY Downstate School of Public Health. &ld...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized bisphenol a BPA endocrine disruptor Environment Environmental Health Source Type: news
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
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