PD-1 + TIGIT + CD8 + T cells are associated with pathogenesis and progression of patients with hepatitis B virus-related hepatocellular carcinoma

In conclusion, PD-1+ TIGIT+ CD8+ T-cell populations are associated with accelerated disease progression and poor outcomes in HBV-HCC, which might not only have important clinical implications for prognosis but also provide a rationale for new targets in immunotherapy.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research