High frequency of anti-parietal cell antibody (APCA) and intrinsic factor blocking antibody (IFBA) in individuals with severe vitamin B12 deficiency – an observational study in primary care patients

Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print
Source: Clinical Chemistry and Laboratory Medicine - Category: Laboratory Medicine Source Type: research

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In conclusion, clinical characteristics of vitamin B12 deficiency are broad and nonspecific and may not be associated with anemia and increased mean corpuscular volume. Since different clinical characteristics can be seen without anemia, awareness and cautious approach are essential in order to avoid severe clinical disease, especially in children from underdeveloped countries. PMID: 31819326 [PubMed - in process]
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
This study assessed whether all BMS patients with ID (so-called ID/BMS patients) had iron deficiency anemia (IDA) and evaluated whether the ID/BMS patients had significantly higher frequencies of anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody (GPCA) positivity than healthy control subjects.Materials and methodsThe blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 143 ID/BMS patients and 442 healthy control subjects were measured and compared.ResultsWe found that 143 ID/BMS patients had significantly lower mean blood Hb and serum i...
Source: Journal of Dental Sciences - Category: Dentistry Source Type: research
VITAMIN B12 is one of the main "raw materials" needed to build the healthy red blood cell; the other is folate or folic acid. In order to make healthy red blood cells that can carry oxygen around the body a person needs adequate levels of B12. Feeling this sensation in your chest is a warning sign of pernicious anaemia.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Good sources of vitamin B12 include low-fat milk, poultry, eggs and fish. → Support PsyBlog for just $4 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Nutrition Source Type: blogs
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
VITAMIN B12 is an essential nutrient that a person ’s body need to perform its vital functions. If left untreated, a vitamin B12 deficiency can cause various health complications and if your skin looks this colour it could be a warning.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Contributors : Jennifer Sloan ; Abdel Elkahloun ; Charles VendittiSeries Type : Expression profiling by arrayOrganism : Danio rerioCobalamin C deficiency (cblC), the most common inborn error of intracellular cobalamin metabolism, is caused by mutations in MMACHC, a gene responsible for the processing and intracellular trafficking of vitamin B12. This recessive disorder is characterized by a failure to metabolize cobalamin into adenosyl- and methylcobalamin, which results in the biochemical perturbations of methylmalonic acidemia, hyperhomocysteinemia, and hypomethioninemia caused by impaired activity of the downstream enzy...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Danio rerio Source Type: research
VITAMIN B12 helps the body to perform a number of vital functions so lacking the vitamin can cause a range of noticeable symptoms. The symptoms usually develop gradually, but can worsen if the condition goes untreated.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
VITAMIN B12 helps the body to perform a number of vital functions so lacking the vitamin can cause a host of unsettling symptoms. Experiencing a certain sensation in your hands may signal you are lacking the vitamin.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
VITAMIN B12 plays an essential role in one ’s overall health. The vitamin is essential in the production of red blood cells and DNA, as well as proper functioning of the nervous system. When the body lacks the vitamin a variety of symptoms can be triggered, including one on a person's tongue.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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