Response to letter by Peng-Wu and Ma on: the relationship of cardiorespiratory fitness and venous thromboembolism: yes or no?
Response to letter by Peng-Wu and Ma on: the relationship of cardiorespiratory fitness and venous thromboembolism: yes or no? Scand Cardiovasc J. 2019 Nov 09;:1-2 Authors: Kunutsor SK, Mäkikallio TH, Laukkanen JA PMID: 31707862 [PubMed - as supplied by publisher]
Conclusion: The overall incidence of VTE is 4% with more than half of events occurred after the stoppage of thromboprophylaxis highlighting the necessity of adopting an extended protocol. Independent predictors included older age, female gender, morbid obesity and preoperative thrombocytosis. These group of patients require particular attention for the prevention of this complication. PMID: 31830847 [PubMed - as supplied by publisher]
In conclusion, chronic or single high dosage exposure to these heavy metals can potentially induce or contribute to thrombosis.
CONCLUSIONS: PELATON is a nuclear expressed, monocyte- and macrophage-specific lncRNA, upregulated in unstable atherosclerotic plaque. Knockdown of PELATON affects cellular functions associated with plaque progression. PMID: 31826651 [PubMed - as supplied by publisher]
Condition: Percutaneous Central Venous Catheter Intervention: Other: Ultrasound scan Sponsor: Assistance Publique - Hôpitaux de Paris Not yet recruiting
Abstract Gossypibomas are uncommon but important complications of surgery. This case report is of a gossypiboma found accidentally 31 years after heart surgery. A 41-year-old man had lost 5 kg in the previous three months and suffered from intermittent epigastric discomfort. A computed tomography scan incidentally revealed a well-defined mass in the right lower anterior mediastinum. Given his history of previous cardiac surgery to repair a ventricular septal defect, the possibility of gossypiboma could not be excluded. Elective excision of the mass was performed through a median sternotomy, and a 5-cm ovoid mass c...
Abstract OBJECTIVE: Netrin-1 has been shown to play a role in the initiation of atherosclerosis in mice models. However, little is known about the role of Netrin-1 in humans. We set out to study whether Netrin-1 is associated with different stages of atherosclerosis. Approach and Results: Plasma Netrin-1 levels were measured in different patient cohorts: (1) 22 patients with high cardiovascular risk who underwent arterial wall inflammation assessment using positron-emission tomography / computed tomography, (2) 168 patients with a positive family history of premature atherosclerosis in whom coronary artery calcium...
AbstractAlmost one third of patients with Beh çet's syndrome (BS) display vascular involvement. However, data regarding the prevalence and management of venous thromboembolism (VTE) in BS are scanty. We assessed the differential characteristics between patients with and without VTE and the factors associated with VTE incidence. A case–contro l study in a cohort of patients with BS was performed. 57 patients were included (56.1% women) with a mean follow-up of 10.56 (± 10.7) years. Mean age at diagnosis of BS and diagnosis of the first VTE episode was 34.7 (± 12.1) and 31.2 (&pl...
Conclusions Despite being a rare condition, Gradenigo syndrome should be taken into account as potential differential diagnosis in children referred to emergency department for recurrent headache and strabismus. An accurate anamnesis to document recent ear infection is mandatory to orientate the diagnosis and focus radiological investigations. Early recognition and timely intervention may allow conservative management to succeed, avoiding the need for surgery and serious sequelae.
Introduction: The risk of stroke is high shortly after the index symptoms in patients with carotid disease. This indicates that unstable carotid plaques stabilizes over time, which may be due to changes in composition and inflammatory activity. Inflammation is thought to be one of the leading causes in atherosclerotic plaques destabilizing leading to thrombosis. With positron emission tomography (PET) previous studies have shown increased uptake of the glucose analogue tracer [18F]-fluorodeoxyglucose (FDG) in symptomatic compared to asymptomatic carotid plaques.
Conclusion: The absence of criteria for endocarditis and negative blood cultures should not keep the physician from ruling out lead endocarditis. This complication carries high risk of mortality if left untreated.