Clinical Course of Preexisting Uveitis during Treatment of Lung Cancer with Durvalumab.
Clinical Course of Preexisting Uveitis during Treatment of Lung Cancer with Durvalumab. Ocul Immunol Inflamm. 2019 Nov 11;:1-5 Authors: Ahmad TR, Doan T, Gonzales JA, Acharya NR, Tsui E PMID: 31710511 [PubMed - as supplied by publisher]
LUNG CANCER is one of the most common and serious types of cancer, with around 47,000 people are diagnosed with the condition every year in the UK. The symptoms associated with lung cancer can have a considerable impact on our daily life and one symptom associated with breathing may make daily tasks more difficult.
CONCLUSIONS: The present meta-analysis provides significant evidence of an inverse association between vegetable and fruit intake and lung cancer risk in current smokers. PMID: 31826375 [PubMed - in process]
CONCLUSIONS: Early supplemental parenteral nutrition after chemotherapy-induced severe granulocytopenia could reduce the risk of infection, improve the likelihood of chemotherapy completion, and shorten hospital stays and leukocyte recovery times. PMID: 31826367 [PubMed - in process]
Condition: Non Small Cell Lung Cancer Interventions: Drug: anti-PD-1 or anti-PD-L1; Drug: EGFR-TKI, ALK inhibitor, ROS1 inhibitor; Drug: investigator decided Sponsor: Shanghai Chest Hospital Recruiting
In this study, A total of 86 lung adenocarcinoma samples paired with adjacent non-tumour tissue samples and eight lung adenocarcinoma non-paired samples were selected for immunohistochemical staining for agrin. Strong staining of agrin in nuclei of lung adenocarcinoma tissues was observed, but not in the nuclei of normal lung tissues (p
We examined LATS2 protein expression by immunohistochemistry in 184 resected NSCLC specimens using tissue microarrays. Low LATS2 expression was significantly related to disease recurrence (p = 0.047). In survival analysis, the low LATS2 expression group showed a statistically poorer overall survival (OS) (p = 0.004) and disease-free survival (DFS) (p = 0.014) than the high expression group. In multivariate analysis, downregulated LATS2 expression in NSCLC could be an independent prognostic factor of poor OS and DFS. Furthermore, we evaluated the prognostic signifi...
In this study, we aimed to investigate the prognostic significance of CD63 expression in non-small cell lung cancer (NSCLC). CD63 expression was evaluated in 133 cases of NSCLC via immunohistochemical staining using tissue microarray blocks. We assessed the relationship between CD63 expression and clinicopathological characteristics, as well as the prognostic significance of CD63 expression in NSCLC. CD63 expression was significantly correlated with patient gender (p
THURSDAY, Dec. 12, 2019 -- Not all patients have access to new, high-cost lung cancer drugs, according to a study recently published in the Journal of the National Cancer Institute. Cathy J. Bradley, Ph.D., from University of Colorado in Aurora, and...
In conclusion, the present study demonstrated that PCAT19 negatively regulates the p53 tumor-suppression pathway, promoting cancer cell proliferation in patients with NSCLC. PMID: 31819778 [PubMed]
Authors: Liu W, Zhang C, Cao H, Shi D, Zhao S, Liang T, Hou G Abstract Lung cancer, especially non-small cell lung cancer (NSCLC), is the most common malignant tumor associated with poor prognosis. Angiogenesis plays a vital role in NSCLC, and could be used in tumor staging and therapy evaluation. CD93 (C1q receptor) is reportedly a key regulator of tumor angiogenesis. In the present study, the efficacy and specificity of a 125I-labeled CD93-specific monoclonal antibody (125I-anti-CD93 mAb) in detecting NSCLC xenografts were analyzed, and the association between CD93 expression and 125I-anti-CD93 mAb uptake by tumo...