New vocabulary for bacterial communication.

New vocabulary for bacterial communication.
Chembiochem. 2019 Nov 11;:
Authors: Tobias NJ, Brehm J, Kresovic D, Brameyer S, Bode HB, Heermann R
Abstract
Quorum sensing (QS) is widely accepted as a procedure that bacteria use to converse. However, prevailing thinking places acyl-homoserine lactones (AHLs) at the forefront of this communication pathway in Gram-negative bacteria. With the advent of high throughput genomics and the subsequent influx of bacterial genomes, bioinformatics analysis has determined that the genes encoding AHL biosynthesis, originally discovered to be indispensable for QS (LuxI-like proteins and homologs), are often absent in QS capable bacteria. Instead, the sensing protein (LuxR-like proteins) is present with an apparent inability to produce any outgoing AHL signal. Recently, several signals for these LuxR solos have been identified. Here, we discuss advances in the field of QS, paying particular attention to recent research in the field of bacterial cell-cell communication.
PMID: 31709676 [PubMed - as supplied by publisher]

Source: Chembiochem - November 10, 2019 Category: Biochemistry Authors: Tobias NJ, Brehm J, Kresovic D, Brameyer S, Bode HB, Heermann R Tags: Chembiochem Source Type: research