Treatment for occult breast cancer: A propensity score analysis of the National Cancer Database

ConclusionsThere were no OS differences in patients undergoing MAST, XRT, or MXRT, suggesting breast conservation can be considered in patients with OBC.
Source: The American Journal of Surgery - Category: Surgery Source Type: research

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Publication date: Available online 5 December 2019Source: The LancetAuthor(s): Frank A Vicini, Reena S Cecchini, Julia R White, Douglas W Arthur, Thomas B Julian, Rachel A Rabinovitch, Robert R Kuske, Patricia A Ganz, David S Parda, Michael F Scheier, Kathryn A Winter, Soonmyung Paik, Henry M Kuerer, Laura A Vallow, Lori J Pierce, Eleftherios P Mamounas, Beryl McCormick, Joseph P Costantino, Harry D Bear, Isabelle GermainSummaryBackgroundWhole-breast irradiation after breast-conserving surgery for patients with early-stage breast cancer decreases ipsilateral breast-tumour recurrence (IBTR), yielding comparable results to m...
Source: The Lancet - Category: General Medicine Source Type: research
Zhang Tam Ho : The purpose of our study was to carry out a meta-analysis of current literature to determine whether total mastectomy and breast-conserving surgery induce different outcomes in quality of life, based on the breast-cancer-specific module of the European Organizaation for Research and Treatment of Cancer core questionnaire (EORTC QLQ-BR23) used postoperatively. A systematic literature search of PubMed and EMBASE was conducted. Observational clinical studies that compared the quality of life in different surgery groups and presented empirical findings were selected. Six studies met the inclusion cri...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
CONCLUSION: Surgically treated breast cancer patients are less likely to receive short- and long-term opioid prescriptions following the implementation of hydrocodone rescheduling. Further studies on the potential impact of federal policy on cancer patient pain management are needed. IMPLICATIONS FOR PRACTICE: Clinicians and researchers with diverse perspectives should be included as stakeholders during policy development for restricting opioid prescriptions. Stakeholders can identify potential unintended consequences early and help identify methods to mitigate concerns, specifically as it relates to policy that influ...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
AbstractPurpose of ReviewContralateral prophylactic mastectomy (CPM) at the time of unilateral breast cancer surgery is increasing, though still controversial in BRCA( −) patients. We review the relevant literature regarding CPM and specifically abnormal imaging/biopsies in patients following unilateral mastectomy (UM) versus CPM and present results from our own retrospective chart review.Recent FindingsA large cohort study by van la Parra et al. examined the incidence/risk of breast biopsy at follow-up, finding the 5-year estimated biopsy rate to be the lowest for UM compared to breast-conserving surgery. Our retros...
Source: Current Breast Cancer Reports - Category: Cancer & Oncology Source Type: research
Publication date: Available online 22 November 2019Source: European Journal of RadiologyAuthor(s): Giovanna Mariscotti, Manuela Durando, Alberto Tagliafico, Pier Paolo Campanino, Davide Bosco, Cristina Casella, Riccardo Bussone, Ada Ala, Isabella Castellano, Anna Sapino, Laura Bergamasco, Paolo Fonio, Nehmat HoussamiAbstractPurposeTo compare the rates of mastectomy and re-operation after breast-conserving surgery(BCS) among patients who had different pre-operative multi-modality imaging, hence identifying significant predictors of mastectomy and re-operations within each group.MethodRetrospective study of consecutive patie...
Source: European Journal of Radiology - Category: Radiology Source Type: research
(NRG Oncology) Approximately 10% of breast cancer patients treated with lumpectomy (breast-conserving surgery [BCS]) and whole-breast radiation (WBI) will have a subsequent in-breast local recurrence of cancer (IBTR) when followed long term.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Conclusions and Relevance: For patients experiencing recurrence of breast cancer in the ipsilateral breast after lumpectomy and whole breast irradiation, a second breast conservation was achievable in 90%, with a low risk of re-recurrence of cancer in the ipsilateral breast using adjuvant partial breast reirradiation. This finding suggests that this treatment approach is an effective alternative to mastectomy. PMID: 31750868 [PubMed - as supplied by publisher]
Source: Ann Oncol - Category: Cancer & Oncology Authors: Tags: JAMA Oncol Source Type: research
AbstractBackgroundNeoadjuvant chemotherapy (NAC) for breast cancer increases breast-conserving surgery (BCS) rates, but many women opt for mastectomy with contralateral prophylactic mastectomy (CPM). Here we evaluate factors associated with CPM use in women undergoing mastectomy post-NAC.MethodsA retrospective institutional NAC database review identified women with clinical stage I-III, unilateral invasive breast cancer undergoing unilateral mastectomy (UM) or CPM mastectomy from 9/2013 to 12/2017. Clinical/pathologic characteristics, imaging, and presence of contraindications to BCS post-NAC were compared, with subset ana...
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
The rate of breast-conserving surgery (BCS) is low in China. Many patients choose mastectomy even when informed that there is no difference in the overall survival rate compared with that of BCS plus radiother...
Source: World Journal of Surgical Oncology - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
We present, 5-year follow-up of QOL scores in breast cancer patients from India.MethodsWe interviewed women undergoing breast cancer surgery preoperatively, at 6  months after surgery, and at 1 year and 5 years, postoperatively. QOL scores were evaluated using FACT B questionnaire. Average QOL scores of women undergoing BCT were compared with those undergoing MRM. Total scores, domain scores and trends of scores over time were analyzed.ResultsWe interviewed 54 women with a mean age of 53  years (SD 9 ± years). QOL scores in all the women, dipped during the treatment period, in a...
Source: Quality of Life Research - Category: Health Management Source Type: research
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