Neuroimaging in Schizophrenia

Publication date: Available online 11 November 2019Source: Neuroimaging Clinics of North AmericaAuthor(s): Matcheri S. Keshavan, Guusje Collin, Synthia Guimond, Sinead Kelly, Konasale M. Prasad, Paulo Lizano
Source: Neuroimaging Clinics of North America - Category: Radiology Source Type: research

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Source: Psychology, Health and Medicine - Category: International Medicine & Public Health Authors: Source Type: research
Social interactions require decoding of subtle rapidly changing emotional cues in others to facilitate socially appropriate behaviour. It is possible that impairments in the ability to detect and decode these signals may increase the risk for aggression. T...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Jurisprudence, Laws, Legislation, Policies, Rules Source Type: news
Psychiatric medications are an important part of treatment for many people with mental disorders, such as depression, bipolar disorder, ADHD, schizophrenia, anxiety, and others. They play an important role in helping to alleviate the most serious symptoms, allowing people to better focus on their lives and on other treatment types, such as psychotherapy. Psychiatric medications are an important part of many people’s treatment plans for obtaining the most effective treatment for a mental health concern or mental illness. It’s good to know what drugs are being prescribed most often for mental disorders in the U.S...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Medications Psychiatry psychiatric meds psychiatric prescriptions Source Type: blogs
Conclusions: Altered activity in the right TPJ supports a disturbance in self/other differentiation in schizophrenia, which could be linked with psychotic symptoms and affect social functioning in patients. Hyperactivity of the lateral frontal cortex for self- and other-reflection suggests the presence of greater cognitive demand to perform the task in the patient group.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Conclusions and RelevanceResults cannot be explained by group differences in DLPFC GABA or glutamate concentrations but, instead, indicate that schizophrenia disrupts the GABAergic facilitation of WM seen in healthy individuals. Results appear to parallel post mortem findings in suggesting that schizophrenia alters the distribution of different classes of GABAergic interneurons rather than producing a general deficit across the total population of neurons.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
ConclusionsCortical volume and cortical thickness deficits are shared between patients with schizophrenia and bipolar disorder, suggesting that both pathologies may be affected by similar environmental and neurodegenerative factors. However, the exclusive alteration in schizophrenia of metrics related to the geometry and curvature of the brain cortical surface (SA, GI) suggests that this group is influenced by additional neurodevelopmental and genetic factors.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Publication date: Available online 13 December 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Julia Kim, Eric Plitman, Yusuke Iwata, Shinichiro Nakajima, Wanna Mar, Raihaan Patel, Sofia Chavez, Jun Ku Chung, Fernando Caravaggio, M. Mallar Chakravarty, Gary Remington, Philip Gerretsen, Ariel Graff-GuerreroAbstractMounting evidence suggests neuroanatomical compromise in subcortical brain regions in patients with schizophrenia. However, only a few existing studies have examined the structural profiles of patients with treatment-resistant schizophrenia. The aim of this study was to compare...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
Publication date: Available online 13 December 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Bianca Besteher, Paolo Brambilla, Igor NenadićAbstractTwin studies in schizophrenia have been crucial in establishing estimates for the heritability and thus providing evidence for a genetic component in this disorder. Recent years have seen the application of the twin study paradigm to both putative intermediate phenotypes and biomarkers of disease as well as a diversification of its use in schizophrenia research. This review addressed studies of brain structure (T1 morphometry) and cognition in schizophrenia usin...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Publication date: Available online 13 December 2019Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Juan Francisco Bada Juarez, Juan C. Muñoz-García, Rosana Inácio dos Reis, Alistair Henry, David McMillan, Marco Kriek, Martyn Wood, Catherine Vandenplas, Zara Sands, Luis Castro, Richard Taylor, Anthony WattsAbstractDopamine receptors (DRs) are class A G-Protein Coupled Receptors (GPCRs) prevalent in the central nervous system (CNS). These receptors mediate physiological functions ranging from voluntary movement and reward recognition to hormonal regulation and hypertension. Drugs tar...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
Authors: von Kodolitsch Y, Demolder A, Girdauskas E, Kaemmerer H, Kornhuber K, Muino Mosquera L, Morris S, Neptune E, Pyeritz R, Rand-Hendriksen S, Rahman A, Riise N, Robert L, Staufenbiel I, Szöcs K, Vanem TT, Linke SJ, Vogler M, Yetman A, De Backer J Abstract Introduction: The revised Ghent nosology presents classical features of Marfan syndrome. However, behind its familiar face, Marfan syndrome hides less well-known features.Areas covered: The German Marfan Organization listed unusual symptoms and clinical experts reviewed the literature on clinical features of Marfan syndrome not listed in the Ghent nosol...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
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