Deep-learning algorithm bolsters lung cancer detection

Radiologists using a deep-learning algorithm can detect more cases of lung...Read more on AuntMinnie.comRelated Reading: Study: public image datasets may have QC issues AI needs robust clinical evaluation in healthcare AI may help improve sensitivity of ED chest x-ray reads Are studies on AI for tuberculosis really valid?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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Over the past 200 years lung diseases have shifted from infections – tuberculosis, pneumonia – to diseases of dirty air – chronic obstructive pulmonary disease, asthma and lung cancer. New diseases have emerged from industrial pollution and HIV infection, while better imaging has revealed others previously unrecognized. Scientific advances in microbiology, im aging and clinical measurement have improved diagnosis and allowed better targeted treatment. Advances in treatment have been dramatic, the most important being drugs (antibiotics, cortisone, β2-adrenoceptor agonists), ventilatory support (from ...
Source: Medicine - Category: Internal Medicine Authors: Tags: Clinical aspects Source Type: research
Publication date: April 2020Source: Cancer Epidemiology, Volume 65Author(s): Faezeh Salamat, Mahmoud Khandashpour, Mohammad Naeimi-Tabiei, Ali Ariannia, Mohammad Ashaari, SeyedMehdi Sedaghat, Fatemeh Ghasemi-Kebria, Fatemeh Salamat, Abbas Moghaddami, Susan Hasanpour-Heidari, Reza Hoseinpour, Nastaran Jafari-Delouei, Hamid Ghayoriardahaei, Masoomeh Gholami, Abdolreza Fazel, Gholamreza Roshandel, Jacques Ferlay, Elisabete WeiderpassAbstractIntroductionWe aimed to present the time trends and geographical distribution of lung cancer in Golestan province, a high-risk area for pulmonary tuberculosis (TB) in Northern Iran (2004-2...
Source: Cancer Epidemiology - Category: Cancer & Oncology Source Type: research
CONCLUSION: This is the first report on the precise efficacy of anlotinib in the treatment of advanced small cell lung cancer. Anlotinib is an important option for patients with small cell lung cancer. PMID: 32031060 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
ConclusionGiven the relatively low incidence of immune ‐related AEs and the comparability of clinical outcomes, ICIs can be treatment option of NSCLC patients with special issues.
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Publication date: Available online 27 January 2020Source: Saudi Journal of Biological SciencesAuthor(s): Ameer Khusro, Chirom Aarti, B. Mahizhaveni, Azger Dusthackeer, Paul Agastian, Galal Ali Esmail, Abdul-Kareem Mohammed Ghilan, Naif Abdullah Al-Dhabi, Mariadhas Valan ArasuAbstractThe present context was investigated to purify and characterize anti-tubercular as well as anticancer protein from fermented food associated Staphylococcus hominis strain MANF2. Initially, the anti-tubercular potency of strain MANF2 was assessed against Mycobacterium tuberculosis H37Rv using luciferase reporter phase assay which revealed pronou...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
A deep-learning algorithm that analyzed chest x-rays was able to predict pulmonary...Read more on AuntMinnie.comRelated Reading: Deep-learning algorithm bolsters lung cancer detection AI may help improve sensitivity of ED chest x-ray reads AI model could speed up pneumonia diagnosis in ED AI detects pulmonary nodules on chest x-rays Are studies on AI for tuberculosis really valid?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
This study provides strong evidence that following a healthy lifestyle can substantially extend the years a person lives disease-free." Commentary on Recent Evidence for Cognitive Decline to Precede Amyloid Aggregation in Alzheimer's Disease https://www.fightaging.org/archives/2020/01/commentary-on-recent-evidence-for-cognitive-decline-to-precede-amyloid-aggregation-in-alzheimers-disease/ I can't say that I think the data presented in the research noted here merits quite the degree of the attention that it has been given in the popular science press. It is interesting, but not compelling if its role...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Underner M, Peiffer G, Perriot J, Jaafari N Abstract Cocaine can be responsible for many psychiatric and/or somatic disorders. The aim of this systematic literature review of data was to expose relations between cocaine use and pulmonary complications. Cocaine can be responsible for acute respiratory symptoms (cough, black sputum, hemoptysis, dyspnea, wheezing, chest pain) and for various pulmonary disorders including barotrauma (pneumothorax, pneumomediastinum, subcutaneous emphysema, pneumopericardium), airway damage, asthma, bronchiolitis obliterans with organizing pneumonia, acute pulmonary edema, alve...
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Abstract Host defense peptides (HDP) are small cationic molecules released by the immune systems of the body, having multidimensional properties including anti-inflammatory, anticancer, antimicrobial and immune-modulatory activity. These molecules gained importance due to their broad-spectrum pharmacological activities, and hence being actively investigated. Presently, respiratory infections represent a major global health problem, and HDP has an enormous potential to be used as an alternative therapeutics against respiratory infections and related inflammatory ailments. Because of their short half-life, protease ...
Source: Current Protein and Peptide Science - Category: Biochemistry Authors: Tags: Curr Protein Pept Sci Source Type: research
The objective of this study was to characterize the metabolic signatures in MPE of lung cancer, and identify potential metabolite biomarkers for diagnosis of MPE. MPE from lung cancer (n = 46) and BPE from tuberculosis patients (n = 32) were investigated by liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based global metabolomic and lipidomic profiling. Multivariate partial least-square discriminative analysis models exhibited distinct metabolic profiles between MPE and BPE. A total of 25 ether lipids, including phosphatidylcholines (PC), lysophosphatidylcholines (LPC) and phosphatidyl...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
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