Up-regulated LINC00261 Predicts a Poor Prognosis and Promotes a Metastasis by EMT Process in Cholangiocarcinoma

ConclusionOverall, high level of LINC00261 in CCA predicts a poor prognosis, and promotes a metastasis via EMT process. Thus, LINC00261 could be a promising biomarker and therapeutic target for CCA, and in the high level of LINC00261 in CCA, E-cadherin or CDH1 might be an effective factor for tumor metastasis or poor prognosis.
Source: Pathology Research and Practice - Category: Pathology Source Type: research