Effects of vitamin D supplements in patients with chronic hepatitis C: a randomized, multi-center, open label study.
Conclusions: Vitamin D supplement did not increase SVR in treatment naïve patients with CHC irrespective of genotype. PMID: 31710801 [PubMed - as supplied by publisher]
Publication date: Available online 12 December 2019Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Jean-Pierre Zarski, Sandra David-Tchouda, Candice Trocme, Jennifer Margier, Antoine Vilotitch, Marie-Noelle Hilleret, Carole Cagnot, Valerie Boursier, Marianne Ziol, Angela Sutton, Richard Layese, Etienne Audureau, Francoise Roudot-Thoraval, Pierre NahonSummaryBackground and AimsMarkers predicting complications of post-hepatitis C cirrhosis are needed. We asked whether changes in noninvasive markers of fibrosis can predict liver-related complications.MethodsThis was a case-controlled study using a pr...
Conclusions: The number of agreements and the allocated budget subject to these agreements increased substantially in recent years. Most agreements are financial-based that, in many cases, shifted the short-term financial risk from health-plans to the industry. PMID: 31825682 [PubMed - as supplied by publisher]
ConclusionsThis real-word experience study confirmed similar, high effectiveness of 8 and 12-weeks regimens of OPrD in genotype 1b HCV infected patients with non-advanced fibrosis. Despite of reduced SVR rate after 8-weeks regimen, there is no need to extend therapy to 12-weeks in vast majority of such patients and no need to add ribavirin.
Leukemia, Published online: 13 December 2019; doi:10.1038/s41375-019-0687-2Interferon-free compared to interferon-based antiviral regimens as first-line therapy for B-cell lymphoproliferative disorders associated with hepatitis C virus infection
ConclusionsClinical testing guidelines have not been effectively translated to practice. Additionally, compared to HIV and HBV, HCV infections during pregnancy are becoming more prevalent, yet current national HCV screening guidelines are the least comprehensive.
Blood tests can usually show whether a person has hepatitis C. However, these tests can give false-positive readings. Here, learn why this can happen.
ConclusionHCV infection was common in certain districts of Punjab and common in adults of 40–60 years. This finding needs to be confirmed in larger population-based study. The IV drug abuse is the risk factor of concern among young adults.
This study modeled the prevention impact achieved from initiating a treat-all policy for HCV compared with treating different subgroups at country, regional and global levels.Journal of Viral Hepatitis
AbstractBackgroundThe ratio of von Willebrand Factor to platelets (VITRO) reflects the severity of fibrosis and portal hypertension and might thus hold prognostic value.MethodsPatients with compensated cirrhosis were recruited. VITRO, Child –Pugh score (CPS) and MELD were determined at study entry. Hepatic decompensation was defined as variceal bleeding, ascites or hepatic encephalopathy. Liver transplantation and death were recorded.ResultsOne hundred and ninety-four patients with compensated cirrhosis (CPS-A 89%, B 11%; 56% male; median age 56 years; 50% with varices) were included. During a median follow-up ...