Racial Bias Seen in Heart Transplants

In the group discussion, black patients were considered less healthy, less likely to comply with follow-up care recommendations and less trustworthy than white patients.
Source: WebMD Health - Category: Consumer Health News Source Type: news

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Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.However, when healing is disrupted — whether by chronic injury or disease — the cells that make up scar tissue can go rogue, continuously dividing and spreading until the scar eventually strangles the organ it was intended to help heal, which can lead to organ failure.That progressive, out-of-control scarring is called fibrosis, and it can occur in any organ in the body. Fibrosis plays a major role in many dis...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Publication date: Available online 9 December 2019Source: Canadian Journal of CardiologyAuthor(s): Eli Muchtar, Grace Lin, Martha GroganAbstractLight chain (AL) amyloidosis is a systemic syndrome characterized by progressive organ dysfunction leading to organ failure and death. The heart is the most commonly involved organ and the leading determinant of short and long-term survival. Pathogenic free light chains, fragments of intact immunoglobulins, are the amyloidogenic protein and are secreted by clonal bone marrow plasma cells. The goal of therapy is to cut-off the supply of these pathogenic light chains to allow organ r...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Condition:   Cardiac Allograft Vasculopathy Interventions:   Drug: Alirocumab;   Other: Placebo Sponsors:   Institute for Clinical and Experimental Medicine;   St. Anne's University Hospital Brno, Czech Republic;   Centre of Cardiovascular and Transplantation Surgery, Czech Republic Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Researchers from Case Western Reserve University in Ohio found those who lived in areas with high pollution levels were 26 per cent more likely to die within 4.8 years of the operation.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Heart transplant recipients living in high pollution areas are more likely to die from infections Related items fromOnMedica Doctors urge people to discuss organ donation Poor patients more likely to die after heart surgery than rich Risk of PE significantly raised well beyond six weeks post-surgery Brexit could result in thousands of extra CVD deaths Rising number of operations cancelled for non-clinical reasons
Source: OnMedica Latest News - Category: UK Health Source Type: news
AbstractObjectiveTo assess interobserver reproducibility of different regions of interest (ROIs) on multi-parametric renal MRI using commercially available software.Materials and methodsHealthy volunteers (HV), patients with heart failure (HF) and renal transplant recipients (Tx) were recruited. Localiser scans, T1 mapping and pseudo-continuous arterial spin labelling (pCASL) were performed. HV and Tx also underwent diffusion-weighted imaging to allow calculation of apparent diffusion coefficient (ADC). For T1, pCASL and ADC, ROIs were drawn for whole kidney (WK), cortex (Cx), user-defined representative cortex (rep-Cx) an...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - Category: Materials Science Source Type: research
AbstractThe calcineurin inhibitor tacrolimus is an effective immunosuppressant and is extensively used in solid organ transplantation. In the first week after heart and lung transplantation, tacrolimus dosing is difficult due to considerable physiological changes because of clinical instability, and toxicity often occurs, even when tacrolimus concentrations are within the therapeutic range. The physiological and pharmacokinetic changes are outlined. Excessive variability in bioavailability may lead to higher interoccasion (dose-to-dose) variability than interindividual variability of pharmacokinetic parameters. Intravenous...
Source: Clinical Pharmacokinetics - Category: Drugs & Pharmacology Source Type: research
MONDAY, Dec. 9, 2019 -- Exposure to air pollution is associated with increased mortality risk after heart transplantation, according to a study published in the Dec. 17 issue of the Journal of the American College of Cardiology. Sadeer G. Al-Kindi,...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
We report the history of a 68-year-old man who underwent implantation of an HeartMate 3TM as a bridge to transplantation. Nineteen months later, he developed signs of heart failure leading to cardiogenic shock. Neither clinical examination nor parameters from the device allowed a clear-cut diagnosis. Only surgical exploration revealed the presence of clots between the polyethylene terephthalate (Dacron®) and polytetrafluoroethylene tubes. This constitutes a weakness of this device for which we propose to the manufacturer for minimal modifications to overcome the problem. PMID: 31814521 [PubMed - as supplied by publisher]
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research
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