Injectable Electrodes for Neuromodulation

Researchers at the University of Wisconsin-Madison have developed an injectable flexible electrode that can aid in neuromodulation therapy, potentially replacing more rigid electrodes that do not mesh well with soft tissues. The injectable material c...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiology Materials Medicine Neurology Neurosurgery Pain Management Sports Medicine Source Type: blogs

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teo D Abstract Background: Altered balance is a common and debilitating symptom of fibromyalgia. Previous studies have investigated balance under single-task conditions that do not reflect real-life situations. The present study evaluated the impact of a simultaneous cell-phone conversation on balance performance in a case-control cohort from Spain. Methods: A cross-sectional case-control study was performed in 34 women recruited from local self-help organizations and university facilities (n = 18 fibromyalgia cases; n = 16 healthy, pain-free controls). Participants performed the 3...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract Neurological diseases particularly Alzheimer's disease (AD), Parkinson's disease (PD), stroke, and epilepsy are on the rise all around the world causing morbidity and mortality globally with a common symptom of gradual loss or impairment of motor behaviour. Striatum, which is a component of the basal ganglia, is involved in facilitating voluntary movement while the cerebellum is involved in the maintenance of balance and coordination of voluntary movements. Dopamine, serotonin, gamma-aminobutyric acid (GABA), and glutamate, to name a few, interact in regulating the excitation and inhibition of motor neuro...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Publication date: 15 January 2020Source: Neuroscience, Volume 425Author(s): Ganne Chaitanya, Walter Hinds, James Kragel, Xiaosong He, Noah Sideman, Youssef Ezzyat, Michael R. Sperling, Ashwini Sharan, Joseph I. TracyAbstractHigh gamma activity (HGA) of verbal-memory encoding using invasive-electroencephalogram has laid the foundation for numerous studies testing the integrity of memory in diseased populations. Yet, the functional connectivity characteristics of networks subserving these memory linkages remains uncertain. By integrating this electrophysiological biomarker of memory encoding from IEEG with resting-state BOLD...
Source: Neuroscience - Category: Neuroscience Source Type: research
In conclusion, the study indicates that MFX relieves a depressive-like state in LPS-induced mice through the inhibition of the NLRP3 inflammasome and the enhancement of the neurogenesis pathway. PMID: 31814820 [PubMed - in process]
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
CONCLUSIONS: Spinal shrinkage equally affects men and women who perform the same work. There are no changes in spinal sagittal alignment throughout the workday in office workers. Office workers increase pain in the upper back significantly at the end of the day. PMID: 31813341 [PubMed - as supplied by publisher]
Source: International Journal of Occupational Safety and Ergonomics - Category: Occupational Health Tags: Int J Occup Saf Ergon Source Type: research
Conclusions: The knowledge about the cause, possible susceptibility, better treatment options, and attitude of the participants were similar to other low-income settings. The negative attitude was high and multidimensional. All stakeholders must work to increase awareness about the cause, symptoms, and treatment options for epilepsy and to decrease the negative attitude of the community. PMID: 31814856 [PubMed - in process]
Source: Behavioural Neurology - Category: Neurology Authors: Tags: Behav Neurol Source Type: research
Publication date: Available online 9 December 2019Source: Pharmacology Biochemistry and BehaviorAuthor(s): Satoshi Deyama, Ronald S. DumanAbstractClinical and preclinical studies have demonstrated that depression, one of the most common psychiatric illnesses, is associated with reduced levels of neurotrophic factors, including brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF), contributing to neuronal atrophy in the prefrontal cortex (PFC) and hippocampus, and reduced hippocampal adult neurogenesis. Conventional monoaminergic antidepressants can block/reverse, at least partially, these ...
Source: Pharmacology Biochemistry and Behavior - Category: Biochemistry Source Type: research
We describe a family ascertained through 3 newborn screening (NBS) positive infants found to be unaffected themselves but in whom the mothers (sisters) were affected. There were also two affected children born to an affected male and his heterozygous wife who were false negatives on NBS but had increased fractional excretion of free carnitine in the urine. Analysis on a Next Generation Sequencing panel specifically designed to fully cover newborn screening disease targets showed a homozygous change in the five probands (SLC22A5; NM_003060:c.-149G > A; p.?). The mutation segregates with the CUD within the family. It ...
Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
Authors: Çınar T, Hayıroğlu Mİ, Çiçek V, Orhan AL PMID: 31813324 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
Authors: Onal Y, Samanci C Abstract BACKGROUND: Hemodynamic depression (HD) is a condition that can be encountered after carotid stenting (CAS) and carotid angioplasty (CAP) due to manipulation of the carotid sinus. The aim of this study was to evaluate whether the carotid bifurcation geometry and angles, or changes in angles, were associated with this HD in patients undergoing CAS and CAP. METHODS: Sixty-two patients with a mean age of 71.1 ± 7.4 years, who underwent CAS and CAP for carotid stenosis were included in the study. HD was defined as periprocedural hypotension (systolic blood pressure
Source: International Angiology - Category: Cardiology Tags: Int Angiol Source Type: research
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