Markedly Effective Steroid Treatment of Three Patients with Allergy-related Jackhammer Esophagus.

Markedly Effective Steroid Treatment of Three Patients with Allergy-related Jackhammer Esophagus. Intern Med. 2019 Nov 08;: Authors: Funaki Y, Ogasawara N, Kawamura Y, Yoshimine T, Tamura Y, Izawa S, Tsuyuki T, Ebi M, Sasaki M, Kasugai K Abstract We experienced marked efficacy with steroid treatment of three patients with jackhammer esophagus (JHE). An esophageal biopsy revealed eosinophilic esophagitis (EoE) in two patients. One of the patients without EoE had eosinophilia and an increased serum immunoglobulin E level, and endoscopic ultrasonography revealed thickening of the esophageal muscularis propria. Esophageal manometry was used to diagnose all cases of JHE. Treatment consisted of steroid administration, which improved the symptoms and resolved the esophageal muscularis propria thickening in all patients. The esophageal manometry findings also normalized following treatment. Allergic diseases, including EoE, were assumed to have caused JHE. PMID: 31708550 [PubMed - as supplied by publisher]
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research

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Funding Opportunity PAR-20-072 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites submission of investigator-initiated Program Project (P01) applications. The proposed programs may address scientific areas relevant to the NIAID mission including the biology, pathogenesis, and host response to microbes, including HIV; the mechanisms of normal immune function system development and function; and immune dysfunction resulting in autoimmunity, immunodeficiency, allergy, asthma, and transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Jörg Kleine-Tebbe, Claudia Mailänder
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Marta Vazquez-Ortiz, Laura Argiz, Adrianna Machinena, Luis Echeverria, Cristina Blasco, Ana Prieto, Sonsoles Infante, Leticia Vila, Emilio Garcia, Purificación Gonzalez-Delgado, Sonia Vazquez-Cortes, Simona Barni, Frederico Martinon-Torres, BIO-FPIES study network
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Yumiko Miyaji, Limin Yang, Kiwako Yamamoto-Hanada, Masami Narita, Hirohisa Saito, Yukihiro Ohya
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 9 December 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Emily H. Liang, Lie H. Chen, Eric MacyAbstractBackgroundLimited population-based data on penicillin-, carbapenem-, monobactam-, and clindamycin-associated reported adverse reactions exists.ObjectiveCollect data on penicillin, carbapenem, monobactam, and clindamycin usage and associated adverse reactions.MethodsData from 1-1-2009 to 12-31-2017 in Kaiser Permanente Southern California was collected.ResultsThere were 6,144,422 unique individuals, mean age 33.6 ± 21.1 years, 52.2% females, with...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Authors: Ring B, Burbank AJ, Mills K, Ivins S, Dieffenderfer J, Hernandez ML Abstract Objectives: Objective measurements of asthma impairment could aid teens in recognition of changes in asthma status over time. Ready access to a conventional spirometer is not realistic outside of the clinical setting. In this proof-of-concept study, we compared the performance of the VitalFlo mobile spirometer to the nSpire KoKo® sx1000 spirometer for accuracy in measuring Forced Expiratory Volume in one second (FEV1) and Forced Vital Capacity (FVC) in adolescents with asthma.Methods: Two hundred forty pulmonary function measu...
Source: Journal of Asthma - Category: Respiratory Medicine Tags: J Asthma Source Type: research
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research
Publication date: 1 January 2020Source: Colloids and Surfaces B: Biointerfaces, Volume 185Author(s): Fazlurrahman Khan, Dung Thuy Nguyen Pham, Sandra Folarin Oloketuyi, Panchanathan Manivasagan, Junghwan Oh, Young-Mog KimAbstractBiofilm formed by several pathogenic bacteria results in the development of resistance against antimicrobial compounds. The polymeric materials present in the biofilm architecture hinder the entry of antimicrobial compounds through the surface of bacterial cells which are embedded as well as enclosed beneath the biofilm matrix. Recent and past studies explored the alternative approaches to inhibit ...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Thought it would be interesting to see how the competitiveness of each field has changed. Percent of applicants who matched to the specialty, listed in order of descending competitiveness: 1. Gastroenterology - 62.8% 2. Pulmonology/Critical Care - 69.5% 3. Rheumatology - 71.3% 4. Cardiovascular Disease - 72.8% 5. Hematology and Oncology - 77.4% 6. Allergy and Immunology - 83.9% 7. Endocrinology - 87.1% 8. Hospice and Palliative Medicine - 87.2% 9. Geriatrics (Internal Medicine) - 90.7% 10... IM subspecialty competitiveness
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Internal Medicine and IM Subspecialties Source Type: forums
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