First-trimester screening for trisomies in pregnancies with a vanishing twin.

CONCLUSION: First-trimester screening for trisomies in vanishing twins should rely on a combination of maternal age, fetal nuchal translucency thickness and serum free β-hCG, as in a singleton pregnancy, without the use of serum PAPP-A. Alternatively, PAPP-A can be included but only after appropriate adjustment for the interval between the estimated gestational age at fetal demise and blood sampling. This article is protected by copyright. All rights reserved.
PMID: 31710734 [PubMed - as supplied by publisher]

Source: The Ultrasound Review of Obstetrics and Gynecology - November 10, 2019 Category: Radiology Authors: Chaveeva P, Wright A, Syngelaki A, Konstantinidou L, Wright D, Nicolaides KH Tags: Ultrasound Obstet Gynecol Source Type: research