A botanical drug composed of three herbal materials attenuates the sensorimotor gating deficit and cognitive impairment induced by MK ‐801 in mice

ConclusionsThese results imply that HCE ameliorates MK ‐801‐induced dysfunctions in prepulse inhibition, social interactions and cognitive function, partly by regulating the Akt and GSK‐3β signalling pathways.

Source: Journal of Pharmacy and Pharmacology - November 11, 2019 Category: Drugs & Pharmacology Authors: Bokyung Koo, Ho Jung Bae, Nayeon Goo, Jaehoon Kim, Jihyun Kim, Mudan Cai, In Ho Jung, Kyungnam Cho, Seo Yun Jung, Suk Woo Chang, Dae Sik Jang, Jong Hoon Ryu Tags: Research Paper Source Type: research