Genotypic divergence of Avibacterium paragallinarum isolates with different growth requirements for nicotinamide adenine dinucleotide.

Genotypic divergence of Avibacterium paragallinarum isolates with different growth requirements for nicotinamide adenine dinucleotide. Avian Pathol. 2019 Nov 11;:1-34 Authors: Jeong OM, Kang MS, Blackall PJ, Jeon BW, Kim JH, Jeong J, Lee HJ, Kim DW, Kwon YK, Kim JH Abstract In 2017, for the first time in Asia, we reported the isolation of variants of Avibacterium paragallinarum with atypical NAD dependency. The present study was conducted to characterize the genotypes of 24 isolates of Av. paragallinarum in Korea, including the four variants reported previously. Most of the typical isolates (19/20) showed a unique ERIC-PCR pattern with no ERIC-PCR patterns in common between the typical isolates and the variants. Furthermore, the variants shared no ERIC-PCR patterns among themselves. All the typical NAD-dependent isolates belonged to the same phylogenetic group based on both 16S rRNA and hagA gene sequences. The four variants were placed in several groups distinct from the typical isolates. In the 16S rRNA phylogenetic analysis, two of the variants were not closely aligned to all other Av. paragallinarum, although they were clearly members of the genus Avibacterium. The other variants were clustered together with NAD atypical isolates from geographically diverse global locations. Compared with the Modesto reference strain AY499870, all the variants lacked a TTTTT stretch at positions 182-186 in the 16S rRNA gene and the same deletion was shown in most of ...
Source: Avian Pathology - Category: Pathology Authors: Tags: Avian Pathol Source Type: research

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Lower respiratory tract infections, such as infections caused by influenza A viruses, are a constant threat for public health. Antivirals are indispensable to control disease caused by epidemic as well as pandemic influenza A. We developed a novel anti-influenza A virus approach based on an engineered single-domain antibody (VHH) construct that can selectively recruit innate immune cells to the sites of virus replication. This protective construct comprises two VHHs. One VHH binds with nanomolar affinity to the conserved influenza A matrix protein 2 (M2) ectodomain (M2e). Co-crystal structure analysis revealed that the com...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Foods may potentially serve as vehicles for the transmission of antimicrobial-resistant variants of Staphylococcus aureus that are important in a human clinical context. Further, retail food products can be a cause of staphylococcal food poisoning. For these reasons and to account for source attribution and risk assessment, detailed information on the population structure, resistance, and virulence profiles of S. aureus originating from retail food products is necessary. In the current study, whole-genome sequences from 88 S. aureus isolates were subjected to bioinformatics analyses in relation to sequence types, antimicro...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
A number of birds at a commercial farm in Suffolk were found to have the H5 strain of avian flu, the Department for Environment, Food and Rural Affairs said on Tuesday.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
BIRD flu has been confirmed on a farm in Suffolk and to limit the risk of the disease spreading a one-kilometre exclusion zone has been set up and nearly 30,000 chickens will be culled. Also known as avian flu, what ’s the risk of humans becoming infected?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Due to an unfortunate oversight the acknowledgements has been omitted.
Source: Journal of Public Health Policy - Category: Health Management Source Type: research
This study also provides important insights into the ecology, epidemiology, and genomic features of gyroviruses in a remote neotropical rainforest. The pathogenesis of this virus in avian species or whether GyV11 can infect humans and/or chickens needs to be further investigated.
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
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Source: OnMedica Latest News - Category: UK Health Source Type: news
Public Health England has said that the risk to public health is very lowCases ofbird flu have been confirmed at a chicken farm in Suffolk, the government has said.All 27,000 birds at the commercial farm will be culled after a number were found to have the H5 type of avian flu, the Department for Environment, Food and Rural Affairs said on Tuesday.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Agriculture Bird flu Health Science Society UK news Source Type: news
Britain's government said bird flu had been confirmed at a chicken farm in eastern England on Tuesday, the first such report since June 2017.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Publication date: Available online 9 December 2019Source: Veterinary Immunology and ImmunopathologyAuthor(s): Qingtao Liu, Jing Yang, Xinmei Huang, Yuzhuo Liu, Kaikai Han, Dongmin Zhao, Lijiao Zhang, Yin LiAbstractAvian influenza subtype H9N2 infection is a mild but highly contagious disease that is associated with a decrease in the efficacy of vaccine interventions, and an increase in susceptibility to secondary infections in poultry. However, the immune evasion mechanism of H9N2 avian influenza viruses (AIVs) in chickens is poorly understood. Dendritic cells (DCs) are immune cells of major importance, involved in innate ...
Source: Veterinary Immunology and Immunopathology - Category: Veterinary Research Source Type: research
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