A Seven-Year Evaluation of Viral Central Nervous System Infections.

In this study, the results of polymerase chain reaction (PCR) for viral agents were evaluated in cerebrospinal fluid (CSF) samples taken from patients with CNS infection. CSF samples taken from 1185 patients between 2010 and 2017 were tested for the presence of Herpes simplex virus (HSV) type 1 and 2, Varicella Zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), adenovirus ve enterovirus by PCR in Dokuz Eylul University Hospital. Tests were performed according to the clinicians' orders and results were evaluated retrospectively. The number of tests performed were 1038 for HSV, 882 for adenovirus, 865 for enterovirus, 496 for VZV, 100 for EBV and 92 for CMV. Commercial tests were used for EBV, CMV (Artus QS-RGQ Kits, Qiagen, Germany) and enterovirus (GeneXpert, Cepheid, USA) while the other viruses (HSV, VZV, adenovirus) were tested by in-house real-time PCR assays. Ninety-one CSF (7.7%) samples were positive. The mean age was 13 (
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research

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Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
[East African] The East African Community Secretariat has signed an agreement that will see the German government fund health and education programmes in the region to the tune of $128 million.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Dozens of species are now at risk but a conference this week will showcase new technology that could help stop the illegal tradeThe two young women who arrived at Heathrow in February 2014 en route to D üsseldorf were carrying nondescript luggage. Customs officers were suspicious nevertheless and looked inside – to find 13 iguanas stuffed into socks inside the cases. Astonishingly, 12 of the highly endangered San Salvador rock iguanas had survived their transatlantic journey.“There only about 600 of these animals left in the wild, in the Bahamas, and these animals were being taken to a private collector so...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Illegal wildlife trade Animals Science Environment Technology Conservation World news Source Type: news
CONCLUSIONS: CMV infection was not associated with impaired long-term prognosis after HT. PMID: 31806387 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
Something is going viral on three University of Wisconsin campuses, and it isn ’t a pretty picture.
Source: Forbes.com Healthcare News - Category: Pharmaceuticals Authors: Source Type: news
María Maximina B. Moreno-Altamirano1*, Simon E. Kolstoe2 and Francisco Javier Sánchez-García1* 1Laboratorio de Inmunorregulación, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Mexico City, Mexico 2School of Health Sciences, University of Portsmouth, Portsmouth, United Kingdom Over the last decade, there has been significant advances in the understanding of the cross-talk between metabolism and immune responses. It is now evident that immune cell effector function strongly depends on the metabolic pathway in w...
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Conclusion: There is a high prevalence of respiratory virus infections in immunocompromised patients undergoing diagnostic bronchoscopy for respiratory symptoms. This finding may influence patient management.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
Immune suppressive therapy after transplantation makes transplant recipients susceptible to a broad range of viral pathogens [1 –6]. Multiple factors can lead to viral reactivation after transplantation, including immune suppressive therapy, graft rejection, inflammation and tissue injury [1,7–11]. The first line therapeutic decision is whether and how to reduce the intensity of immune suppression, because the risk of th is therapy is graft rejection [1,12]. Several viruses including adenoviruses, cytomegalovirus (CMV), Epstein-Barr virus (EBV), enteroviruses, herpes simplex virus type 1 (HSV-1), herpes simplex...
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research
AbstractDespite increased understanding of how viral infection is involved in asthma exacerbations, it is less clear which viruses are involved and to what extent they contribute to asthma exacerbations. Here, we sought to determine the prevalence of different respiratory viruses during asthma exacerbations. Systematic computerized searches of the literature up to June 2017 without language limitation were performed. The primary focus was on the prevalence of respiratory viruses, including AdV (adenovirus), BoV (bocavirus), CoV (coronavirus), CMV (cytomegalovirus), EnV (enterovirus), HSV (herpes simplex virus), IfV (influe...
Source: Archives of Virology - Category: Virology Source Type: research
aacute;č A Abstract Central nervous system is protected by the blood-brain barrier, which represents a physical, metabolic and transport barrier and is considered to be a part of a highly dynamic system termed neurovascular unit. Several pathogens, among them viruses, are able to invade the brain. Traversal of viruses across the blood-brain barrier is an essential step for the invasion of the central nervous system and can occur by different mechanisms - by paracellular, transcellular and/or by "Trojan horse" pathway. Penetration of viruses to brain can lead to the blood-brain barrier dys...
Source: Acta Virologica - Category: Infectious Diseases Authors: Tags: Acta Virol Source Type: research
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