Are proton pump inhibitors among the risk factors for acute coronary syndrome? A multi-centric case-control study between patients attending governmental hospitals in western Saudi Arabia.

CONCLUSIONS: There was no association between PPIs and the occurrence of a first non-fatal ACS event. Smoking, increased weight, and dyslipidemia are considered predictors of ACS. Furthermore, ACS is associated with self-reported diabetes, hypertension, and physical activity. PMID: 31707405 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research

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Publication date: Available online 5 November 2019Source: Indian Heart JournalAuthor(s): Sreenivas Reddy, Suraj Kumar, Jeet Ram Kashyap, Raghavendra Rao, Vikas Kadiyala, Hithesh Reddy, Naindeep Kaur, Vadivelu Ramalingam, Jaspreet KaurAbstractObjectiveThe coronary artery dimensions have important diagnostic and therapeutic implications in management of coronary artery disease (CAD). There is paucity of data on the coronary artery size in the Indian population as measured by intravascular ultrasound (IVUS).MethodsA total of 303 patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) wi...
Source: Indian Heart Journal - Category: Cardiology Source Type: research
K. H. Alanazi et al.
Source: Emerging Infectious Diseases Journal - Category: Infectious Diseases Source Type: research
Publication date: Available online 9 December 2019Source: Biochimica et Biophysica Acta (BBA) - BiomembranesAuthor(s): Sofia Kiriakidi, Christos Chatzigiannis, Christina Papaemmanouil, Andreas G. Tzakos, Thomas MavromoustakosAbstractCardiovascular diseases and hypertension in particular are major health risks worldwide and the improvement on their treatment will be beneficial for the human health. AT1R antagonists belong to the sartans family that targets the renin-angiotensin aldosterone system (RAAS) through blocking the hormone angiotensin II to exert its detrimental effects in pathological states. As a consequence, the...
Source: Biochimica et Biophysica Acta (BBA) Biomembranes - Category: Biochemistry Source Type: research
Journal of Human Hypertension, Published online: 10 December 2019; doi:10.1038/s41371-019-0294-8Associations between primary aldosteronism and diabetes, poor bone health, and sleep apnea—what do we know so far?
Source: Journal of Human Hypertension - Category: Cardiology Authors: Source Type: research
Publication date: Available online 9 December 2019Source: Canadian Journal of DiabetesAuthor(s): Lingning Huang, Yongze Zhang, Yunmin Wang, Ximei Shen, Sunjie YanAbstractAimsInvestigate association between diabetic peripheral neuropathy (DPN)and above normal blood pressure in non-hypertensive patients with type 2 diabetes mellitus(T2DM). Compare the achievement of clinical target for DPN and non-DPN withT2DM .MethodsA retrospective survey was administered to 3810 patients with type 2 diabetes. Cases were grouped according to the Toronto Clinical Scoring System (TCSS): Non-DPN, Mild DPN, Moderate DPN and Severe DPN. 1835 pa...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
AbstractFew studies have addressed the predictive value of arterial stiffness determined by pulse wave velocity (PWV) in a high-risk population with no prevalent cardiovascular disease and with obesity, hypertension, hyperglycemia, and preserved kidney function. This longitudinal, retrospective study enrolled 88 high-risk patients and had a follow-up time of 12.4  years. We collected clinical and laboratory data, as well as information on arterial stiffness parameters using arterial tonometry and measurements from ambulatory blood pressure monitoring. We considered nonfatal, incident cardiovascular events as the prima...
Source: Journal of Medical Systems - Category: Information Technology Source Type: research
AbstractCardiovascular diseases (CVD) are one of the leading causes of death worldwide. Testosterone (T) is an important sex hormone that triggers several genomic and non-genomic pathways, leading to improvements of several cardiovascular risk factors and quality of life in men. At the vascular level, the key effect of T is the vasorelaxation. This review discusses the molecular pathways and clinical implications of T in the vascular system. Firstly, the mechanisms involved in the T vasodilator effect will be presented. Then, it will be discussed the association of T with the main risks for CVD, namely metabolic syndrome, ...
Source: Journal of Cardiovascular Translational Research - Category: Cardiology Source Type: research
SummaryTo examine the trends in chronic conditions after accounting for temporal differences in body mass index (BMI) and waist circumference (WC). Pooled cycles (1999 ‐2014) of the U.S. National Health and Nutrition Examination Survey (NHANES) were analysed (n = 36 959). The models were adjusted for caloric intake, smoking, medications use and physical activity. The prevalence of diabetes increased in women with general or abdominal obesity (BMI*time; WC*time ,P   .05), whereas for a given WC, there was a decrease in the prevalence over time in women (WC*time,P = .05). For dyslipidemia, independent ...
Source: Clinical Obesity - Category: Eating Disorders & Weight Management Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
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Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
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Source: Endocrine - Category: Endocrinology Source Type: research
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