Patients reveal how they have reaped remarkable benefits of stem cells

Stem cells are the human body's raw material for repairing itself. They can self-renew or turn into a specific type of cell, such as blood or muscle. They have a range of benefits for treating conditions.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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Editor ’s PerspectiveWhat We Already Know about This TopicSepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection for which there is no direct treatmentMesenchymal stromal cells have potent immunomodulatory, proreparative, and regenerative properties and have potential as therapeutics for sepsisMesenchymal stromal cells enhance bacterial killing by augmenting macrophage functionWhat This Article Tells Us That Is NewIn a rat model of fecal peritonitis, human umbilical cord mesenchymal stromal cells improved survival and reduced bacterial load by enhancing peritone...
Source: Anesthesiology - Category: Anesthesiology Source Type: research
Stem Cells and Development, Ahead of Print.
Source: Stem Cells and Development - Category: Stem Cells Authors: Source Type: research
Behçet's syndrome (BS) is a systemic vasculitis considered as the prototype of a systemic inflammation-induced thrombotic condition whose pathogenesis cannot be explained just by coagulation abnormalities. Circulating hematopoietic progenitor cells (CPC), a population of rare, pre-differentiated adult stem cells originating in the bone marrow and capable of both self-renewal and multi-lineage differentiation, are mobilized in response to vascular injury and play a key role in tissue repair. In cardiovascular and thrombotic diseases, low circulating CPC number and reduced CPC function have been observed. Oxidative st...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Regenerative Medicine, Ahead of Print.
Source: Future Medicine: Regenerative Medicine - Category: Genetics & Stem Cells Authors: Source Type: research
This article aimed to investigate effects of exosomes secreted from miRNA-29b-modified bone marrow mesenchymal stem cells (BMSCs) on SCI. Exosomes were extracted from BMSCs transfected with miRNA-29b or negative control (miR NC). SCI rats were injected intravenously with exosomes (control exosomes, miRNA-29b exosomes) and BMSCs (miR NC, miRNA-29b) through the tail vein. The expression of miRNA-29b in spinal cord tissues of SCI rats was detected by qRT-PCR. The hind limb motor function was evaluated by Basso Beattie Bresnahan (BBB) score. The histopathological damage and neuronal regeneration in spinal cord tissues was obse...
Source: Braz J Med Biol Res - Category: Research Authors: Tags: Braz J Med Biol Res Source Type: research
To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.
Source: The Scientist - Category: Science Tags: News & Opinion Source Type: news
Conditions:   Acute Leukemia;   Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Adult Diffuse Large Cell Lymphoma;   Anaplastic Large Cell Lymphoma;   Burkitt Lymphoma;   Chronic Myelogenous Leukemia, BCR-ABL1 Positive;   Chronic Myelomonocytic Leukemia;   Hodgkin Lymphom a;   Lymphoblastic Lymphoma;   Lymphoplasmacytic Lymphoma;   Mantle Cell Lymphoma;   Mixed Phenotype Acute Leukemia;   Myelodysplastic Sy...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Familial haploidentical stem-cell transplant improves outcomes in children and adolescents with high-risk sickle-cell disease, researchers report.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
Co-founded by World-Renowned Stem Cell Scientist Jeanne F. Loring, Ph.D. and Andres Bratt-Leal, Ph.D. Led by Chief Executive Officer Howard Federoff, M.D., Ph.D., Former Vice Chancellor for Health Affairs and Chief Executive Officer of the University of... Regenerative Medicine, Neurology, Venture Capital Aspen Neuroscience, cell therapy, Parkinson's disease
Source: HSMN NewsFeed - Category: Pharmaceuticals Source Type: news
Publication date: Available online 10 December 2019Source: The LancetAuthor(s): Maria-Victoria Mateos, Michele Cavo, Joan Blade, Meletios A Dimopoulos, Kenshi Suzuki, Andrzej Jakubowiak, Stefan Knop, Chantal Doyen, Paulo Lucio, Zsolt Nagy, Ludek Pour, Mark Cook, Sebastian Grosicki, Andre Crepaldi, Anna Marina Liberati, Philip Campbell, Tatiana Shelekhova, Sung-Soo Yoon, Genadi Iosava, Tomoaki FujisakiSummaryBackgroundStandard-of-care treatment for patients with newly diagnosed multiple myeloma includes combination therapies for patients who are not eligible for autologous stem-cell transplantation. At the primary analysis ...
Source: The Lancet - Category: General Medicine Source Type: research
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