Stromal-Immune Score-Based Gene Signature: A Prognosis Stratification Tool in Gastric Cancer

Conclusion: The stromal-immune score-based gene signature represents a prognosis stratification tool in gastric cancer.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research

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Conditions:   Subjects With Resectable and Localized Gastric Cancer;   Subjects With Resectable Esophageal Cancer or Liver Cancer;   Subjects With Resectable Liver Cancer Intervention:   Drug: IMC-001 Sponsor:   Asan Medical Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Advanced Gastric Cancer Interventions:   Drug: Camrelizumab;   Drug: Apatinib Mesylate;   Drug: Docetaxel;   Drug: S1 Sponsor:   Fujian Medical University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Metastatic invasive lobular carcinoma (mILC) may masquerade as primary diffuse gastric adenocarcinoma (PDGA) by demonstrating significant clinical and pathologic overlap. Accurate distinction is of therapeutic and prognostic significance. On the basis of anecdotal cases of mILC that lacked estrogen receptor and/or GATA3 expression, we analyzed the cytoarchitectural features of 28 mILC and 44 PDGA specimens obtained from women to assess features that would help in this distinction and prompt ancillary work-up. In addition to performing an interobserver agreement analysis among 3 pathologists, we also evaluated SATB2 express...
Source: The American Journal of Surgical Pathology - Category: Pathology Tags: Original Articles Source Type: research
Publication date: Available online 10 December 2019Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Juan Li, Qingli Wang, Yichao Zheng, Piao Zhou, Xia Xu, Xueqi Liu, Longfei Zhao, Hongmin LiuAbstractGastric cancer (GC) is the third most common cause of cancer death worldwide, and the incidence of GC is higher in males than females. To investigate the gastric cellular response to hormone therapy, we developed a cell pseudotargeted metabolomics method based on liquid chromatography-hybrid triple quadrupole linear ion trap mass spectrometry (LC-QTRAP MS). Chromatographic separation, sample analysis and meta...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
Authors: Kume K, Nishizuka SS Abstract Understanding cellular heterogeneity is a challenge for cell biology, particularly in the fields of stem cell and cancer biology. We recently established a reverse phase protein array (RPPA)-modified method, colony lysate array (CoLA), which enables proteomic profiling of individual subpopulations (i.e., colonies) derived from various cell proliferative conditions. Here we describe two independent CoLA assays for a functional subpopulation, drug-tolerant persisters (DTPs), which are considered to mimic the origin of chemotherapeutic cancer relapse. In the first study, we analy...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
Cancer Gene Therapy, Published online: 12 December 2019; doi:10.1038/s41417-019-0153-3MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells
Source: Cancer Gene Therapy - Category: Cancer & Oncology Authors: Source Type: research
ConclusionConsequently, the rs1179251, rs2227485, rs2227511, and rs2227473 polymorphisms may not be associated with cancer risk. However, further investigations using larger samples in different ethnic populations are required.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
The authors would like to correct the error in the publication of the original article. The correction detail is given below:
Source: Gastric Cancer - Category: Gastroenterology Source Type: research
We present two cases which are specific for unusual location of Burkitt lymphoma in the colon and stomach, in immunocompetent patients with negative Epstein-Barr virus tests. Also, one of the patients presented is one of the oldest ever reported with abdominal Burkitt lymphoma, while the other patient is an example of diagnostic difficulties in distinguishing Burkitt lymphoma from similar lymphomas. Due to the rapidly growing tumors and urgent need for cytoreductive surgery, it is crucial to consider the diagnosis of Burkitt lymphoma even in atypical localizations or absence of the common risk factors associated with Burki...
Source: Acta Clinica Croatica - Category: General Medicine Tags: Acta Clin Croat Source Type: research
Conditions:   Esophageal Adenocarcinoma;   Gastric Adenocarcinoma Intervention:   Other: ChemoFit exercise prehabilitation intervention Sponsors:   Newcastle-upon-Tyne Hospitals NHS Trust;   Newcastle University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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