Genetic Markers in Psychiatry.

Genetic Markers in Psychiatry. Adv Exp Med Biol. 2019;1192:53-93 Authors: Nedic Erjavec G, Svob Strac D, Tudor L, Konjevod M, Sagud M, Pivac N Abstract Psychiatric disorders such as addiction (substance use and addictive disorders), depression, eating disorders, schizophrenia, and post-traumatic stress disorder (PTSD) are severe, complex, multifactorial mental disorders that carry a high social impact, enormous public health costs, and various comorbidities as well as premature morbidity. Their neurobiological foundation is still not clear. Therefore, it is difficult to uncover new set of genes and possible genetic markers of these disorders since the understanding of the molecular imbalance leading to these disorders is not complete. The integrative approach is needed which will combine genomics and epigenomics; evaluate epigenetic influence on genes and their influence on neuropeptides, neurotransmitters, and hormones; examine gene × gene and gene × environment interplay; and identify abnormalities contributing to development of these disorders. Therefore, novel genetic approaches based on systems biology focused on improvement of the identification of the biological underpinnings might offer genetic markers of addiction, depression, eating disorders, schizophrenia, and PTSD. These markers might be used for early prediction, detection of the risk to develop these disorders, novel subtypes of the diseases and tailored, personalized approach t...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research

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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction General Mental Health and Wellness Not Crazy Podcast Recovery Source Type: blogs
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Source: International Journal of Law and Psychiatry - Category: Medical Law Authors: Tags: Int J Law Psychiatry Source Type: research
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Source: Neuropharmacology - Category: Drugs & Pharmacology Authors: Tags: Neuropharmacology Source Type: research
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Inside Schizophrenia Men's Issues Psychiatry Psychology Living With Schizophrenia Mental Disorder Mental Health Mental Illness Symptoms Of Schizophrenia Source Type: blogs
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Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism alcohol abuse alcohol treatment alcohol treatment center Source Type: blogs
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Source: Psychiatria Polska - Category: Psychiatry Tags: Psychiatr Pol Source Type: research
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Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized health Source Type: news
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Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Policy and Advocacy Relationships The Psych Central Show Source Type: blogs
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Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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