Evaluation of a Palliative Care Program for Nursing Homes in 7 Countries

This cluster-randomized clinical trial examines the effect of implementing the Palliative Care for Older People Steps to Success Program in 78 nursing homes in 7 countries with residents and staff outcomes at resident end of life.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research

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In conclusion, depletion of vancomycin-sensitive bacteria enhances the antitumor activity of RT, which has important clinical ramifications.
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
My brother and I are both physicians. He is a pediatrician; I am a geriatrician and palliative medicine doctor. We are both getting older. My brother has been a practicing pediatrician for almost 50 years. He had a remarkably successful solo practice in the city where he lived. He recently retired but continued to work […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Physician Geriatrics Primary Care Source Type: blogs
This study investigated the effect of a combination of atypical Protein Kinase C (PKC) inhibitor (either ICA-I or ζ-Stat) and 5-FU (a thymidylate synthase inhibitor) on CRC cells viability concerning cellular DNA damage. In this study, we took multiple approaches such as colony formation assay, flow cytometry, DNA ladder assay, TUNEL assay, etc. to examine the CRC cell viability and apoptosis as a function of combination treatment. Our findings showed that the combination of atypical PKC inhibitor and 5-FU synergistically reduced the viability of CRC cells and induced apoptosis. Additionally, the DNA ladder and TUNEL ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
(University of Vermont) Researchers at the University of Vermont's Vermont Conversation Lab have used machine learning and natural language processing to better understand what end-of-life conversations look like. Borrowing techniques used to study fiction, where machine learning algorithms analyze manuscripts to identify story types, the researchers identified several common elements in these conversations. That knowledge could eventually help healthcare practitioners understand what makes a 'good' conversation about palliative care.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Discussion Gaucher disease (GD) was first described by Philippe Gaucher in 1882. It was the first lysosomal storage disease (LSD) described and is the comparison prototype for many variations and their treatment. There are about 50 LSD and more well-known ones include Fabry, Niemann-Pick and Pompe diseases. LSDs currently have more than 300 different enzymes or membrane proteins affected which cause central nervous system and visceral disease. Overall the frequency of LSDs in aggregate is 1:3000 – 7000 live births. GD has an estimated prevalence of 1:57,000 – 111,000. It is higher within the Ashkenazi Jewish po...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Conclusion: There is a rethinking of treatment behavior in children with trisomy 18. The possible quality of life achieved should be further investigated. It seems inappropriate to simply dismiss medical interventions.What is Known•Until recently, trisomy 18 was considered a disease incompatible with life. The most common behavior was abortion and denial of treatment.What is New•It is no longer considered a lethal disease. The type of medical intervention that is appropriate to perform is now being discussed. Selected children benefit from an interventionist approach.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
Sexual and gender minority older adults face unique challenges in health care and are at greater risk for poor health outcomes. The aging population is growing significantly. Nurse practitioners have an opportunity to address the specific challenges associated with family and social support, unique relationships, sexuality and its implications, the lack of community resources, housing including long-term care, end-of-life and palliative care disparities for these populations.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Feature Article Source Type: research
Authors: Draghici G Abstract The infertility of the couple represents a constant preoccupation of the modern society; the supervision of the fertility of the population has become a necessity today, as a result of the behaviour and habitat modifications, which the modern life has generated. Today the PMA (Assisted Human Reproduction) techniques allow the palliative solving of the medical problems, as far as the somatic plan is concerned, the incapacity of procreation of the couple. However, beyond the attempt of practically solving infertility, at the world level, the specialists in the field of reproduction have p...
Source: Journal of Medicine and Life - Category: General Medicine Tags: J Med Life Source Type: research
Thought it would be interesting to see how the competitiveness of each field has changed. Percent of applicants who matched to the specialty, listed in order of descending competitiveness: 1. Gastroenterology - 62.8% 2. Pulmonology/Critical Care - 69.5% 3. Rheumatology - 71.3% 4. Cardiovascular Disease - 72.8% 5. Hematology and Oncology - 77.4% 6. Allergy and Immunology - 83.9% 7. Endocrinology - 87.1% 8. Hospice and Palliative Medicine - 87.2% 9. Geriatrics (Internal Medicine) - 90.7% 10... IM subspecialty competitiveness
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Internal Medicine and IM Subspecialties Source Type: forums
Opioids are high-risk medicines used in high doses and volumes in specialist palliative care inpatient services to manage palliative patients ’ pain and other symptoms. Despite the high volume of opioid use in this care setting, serious errors with opioids are exceedingly rare. However, little is known about the factors that mitigate opioid errors in specialist palliative care inpatient services.
Source: Collegian - Category: Nursing Authors: Source Type: research
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