Overuse and Misuse of Inhaled Corticosteroids Among Veterans with COPD: a Cross-sectional Study Evaluating Targets for De-implementation

ConclusionsPotentially inappropriate ICS use is common among patients with and without airflow obstruction who are diagnosed with COPD. We identified patient comorbidities and patterns of healthcare utilization that increase the likelihood of ICS use that could be targeted for system-level de-implementation interventions.
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research

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Publication date: Available online 4 December 2019Source: Joint Bone SpineAuthor(s): Chang-Fu Kuo, Patricia B. Burns, Jung-Sheng Chen, Lu Wang, Kevin C. ChungAbstractObjective: The purpose of the study is to investigate the risk of preventable hospitalization among patients with rheumatoid arthritis (RA).Methods: We identified 11,852 incident RA patients and 59,260 age-, sex-, and index year-matched controls from the Taiwan National Health Insurance Database. Index date was the RA diagnosis date for cases, which was assigned to their matched controls. The odds ratios (OR) of preventable hospitalizations between RA patients...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
nge P Abstract RATIONALE: Identification of younger adults at high risk of developing chronic obstructive pulmonary disease (COPD) could lead to implementation of preventive measures before disease onset and halt progression. OBJECTIVE: To investigate the prevalence, characteristics, and prognosis of individuals with early COPD in the general population. METHODS: We investigated 105 630 randomly chosen adults from a Danish contemporary population-based cohort. Early COPD was defined as forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC)
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
Sleep apnea lead to sudden death associated with breathing during sleep(Kim et.al,2015)Aim: To investigate sleep apnea status and related factors in patients with respiratory failureMethod: The sampleof study consists of 86 people who received treatment in chest clinic and voluntarily agreed to participate. Data were collected by using interview form with sociodemographic characteristics, Pittsburg Sleep Quality Index, Berlin Sleep Apnea IndexResult: The mean age was 58±12, 66,3%were male, 55.8%had quit smoking due to disease.54.7%of the participants had COPD,26.7% had pneumonia,10.5%had asthma. 67.4%of patients had...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory function technologists/scient. Source Type: research
Conclusions: Respiratory symptoms are associated with subsequent respiratory hospitalisations and death in individuals with preserved pulmonary function without known airway disease.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Conclusion: The determinants of suitability for HD-ICS prescription in primary care records are inconsistently recorded, difficult to identify and challenging to apply.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: General practice and primary care Source Type: research
This study aims to determine etiology and clinical features of bronchiectasis in Taiwan.This multi-center cohort study investigated non-CF bronchiectasis patients newly diagnosed from 2002/1/1 to 2016/12/31. The clinical data was retrieved from five medical centers across Taiwan. The index date was bronchiectasis firstly diagnosed. Known diseases that existed before the index date were regarded as etiologies of bronchiectasis.A total of 15,729 adult patients with bronchiectasis were included. Idiopathic (32%) was the most common cause, followed by post-pneumonia (24%). Other causes included post-tuberculosis (12%), chronic...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Conclusion: In patients with COPD, we considered that attention to the onset of LC should be paid regardless of the background factors. In patients with COPD, it was effective to perform chest CT once a year for early detection and treatment of LC.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring airway disease Source Type: research
Introduction: Inhaled corticosteroids (ICS) are effective in exacerbations prevention in patients with obstructive lung diseases. They were also related to increased risk of pneumonia. The aim of this study was to evaluate the effect on exacerbations of inhaled corticosteroids in a bronchiectasis population before a specialized study at a bronchiectasis clinic.Methods: Retrospective cohort study from Centro Hospitalar de Leiria (Portugal). Sample was divided into patients on previous ICS treatment (G1) and ICS naive group (G0). General demographics, microbiologic profile, lung function, comorbidities and exacerbation rate ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections Source Type: research
Conclusions: Physician-diagnosed ACO patients had highest prevalence of current-smoker and their symptoms, lung function, and eosinophil counts were between the two conditions.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Airway pharmacology and treatment Source Type: research
Introduction: Patients with chronic obstructive pulmonary disease (COPD) have higher risk of hospitalization for cardiovascular events (CVE). An association between influenza infection and myocardial infarction (MI) is established. Our objective is to evaluate the COPD as an additional risk factor for CVE and respiratory events (RE) in patients with respiratory viral infection.Methods: We performed a retrospective cross-sectional analysis of 139 patients, with positive PCR for respiratory viruses in January of 2018. Cardiovascular risk factors (CVRF) (hypertension, diabetes, dyslipidemia and smoking) and medical history we...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Monitoring airway disease Source Type: research
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