What is the most useful body composition parameter for predicting toxicities of preoperative chemotherapy for gastric cancer?
ConclusionsPatients with a low PMI experienced an increased incidence of hematological and non-hematological toxicities during preoperative chemotherapy for gastric cancer. Clinicians should be aware of these risks in this population.
Conclusions: Hyperthermia increased the serum neutrophil-recruiting cytokine levels and reduced the magnitude of chemotherapy-induced neutropenia. Thus, HIPEC improved neutrophil and bone marrow recovery compared with conventional IP chemotherapy. PMID: 31818168 [PubMed - in process]
Chem. Commun., 2019, Accepted Manuscript DOI: 10.1039/C9CC08498C, CommunicationPeng Gao, Mingwan Shi, Ruyue Wei, Wei Pan, Xiaohan Liu, Na Li, Bo Tang A homotypic cancer cell membrane camouflaged MOF-based nanoreactor with the photothermal-starvation effect has been developed for synergistic suppression of intracellular defensive systems for enhanced cancer treatment. The content of this RSS Feed (c) The Royal Society of Chemistry
Authors: Laganà AS, Garzon S, Raffaelli R, Ban Frangež H, Lukanovič D, Franchi M PMID: 31818165 [PubMed - as supplied by publisher]
Authors: Wang J, Zhang Y, Lu X, Xi C, Yu K, Gao R, Bi K Abstract Background: Idiopathic granulomatous mastitis (IGM) can clinically and radiographically mimic an abscess or breast cancer. Although IGM is benign, it can cause the breast skin to appear "riddled with holes" and can even result in the loss of the breast. The optimal treatment has not been established. Methods: We retrospectively studied the medical records of 200 patients with IGM who were treated for skin rupture from June 2015 to June 2017 in our institute. The patients' treatment modalities (including surgery after steroid therapy and ster...
[This Day] Martins Ifijeh chronicles the life of a young ambitious Nigerian woman who was diagnosed with breast cancer, but due to ignorance and high cost of treatment, opted for herbal treatment in Jos, as against orthodox treatment, which then worsened her condition. She was however lucky to retrace her steps on time, and she is presently accessing proper healthcare in Abuja
[This Day] Abuja -Over 5,000 persons have benefited from diabetes, hypertension, cervical and breast cancer free screening, which was facilitated by MITEDA Wellness Initiative, a nongovernmental organisation and in collaboration with the Lagos State government.
Authors: Buckley E, Roder DM PMID: 31821555 [PubMed - as supplied by publisher]
Authors: Kim ST, Lee J, Lee SJ, Park SH, Jung SH, Park YS, Lim HY, Kang WK, Park JO Abstract We designed a single-arm, open label phase II study to determine the efficacy and toxicity of the combination of pazopanib with CapeOx (capecitabine and oxaliplatin) in metastatic /recurrent advanced gastric cancer (AGC) patients. Previously untreated AGC patients received capecitabine (850 mg/m2 bid, day 1-14) plus oxaliplatin (130 mg/m2, day 1) in combination with pazopanib (800 mg, day 1-21) every three weeks. Treatment was continued until progression of the disease or intolerable toxicity was observed. In all, 66 patien...
This study was registered on ClinicalTrials. Gov, number NCT01198392. A total of 236 patients were enrolled. Median TTP was 5.51 months in CS group compared with 4.62 months in CF group [hazard ratio (HR) 1.028, 95% confidential interval (CI) 0.758-1.394, p = 0.859]. Median OS was 10.00 months and 10.46 months in CS and CF groups (HR 1.046, 95%CI 0.709-1.543, p = 0.820), respectively. The most common adverse events in both groups were anemia, leukopenia, neutropenia, nausea, thrombocytopenia, vomiting, anorexia and diarrhea. We find that S-1 plus cisplatin is an effective and tolerable option for advanced gastric or gastro...