Can we predict intraoperative blood loss in meningioma patients? Application of dynamic susceptibility contrast-enhanced magnetic resonance imaging

Publication date: Available online 10 November 2019Source: Journal of NeuroradiologyAuthor(s): Yeonah Kang, Kuo-Chen Wei, Cheng Hong TohAbstractPurpose: To evaluate the potential of quantitative dynamic susceptibility contrast (DSC) perfusion MR imaging parameters as imaging biomarkers for predicting intraoperative blood loss in meningioma.Methods: Fifty-one non-embolized meningioma patients who had undergone preoperative DSC perfusion MR imaging were retrospectively included. The corrected relative cerebral blood volume (rCBV) and leakage coefficient (K2) of the entire enhanced tumor were obtained using leakage correction. Tumor volume, location, grade, and other clinical variables, were also analyzed. To investigate the vascularity and vascular permeability of meningiomas, and their correlation with predicting estimated blood loss (EBL) using preoperative DSC perfusion MR imaging, the authors proposed an index reflecting the inherent tendency of meningiomas to bleed after controlling volume (i.e., EBL/cm3). Simple regression was performed to identify predictors of EBL/cm3; subsequently, the relevant variables included in the stepwise multiple linear regression.Results: On univariate analysis, EBL/cm3 was correlated with rCBV (r=0.677; p
Source: Journal of Neuroradiology - Category: Radiology Source Type: research

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Publication date: Available online 5 December 2019Source: American Heart JournalAuthor(s): Odayme Quesada, Ahmed AlBadri, Janet Wei, Chrisandra Shufelt, Puja K. Mehta, Jenna Maughan, Nissi Suppogu, Haider Aldiwani, Galen Cook-Wiens, Michael D. Nelson, Behzad Sharif, Eileen M. Handberg, David R. Anderson, John Petersen, Daniel S. Berman, Louise E.J. Thomson, Carl J. Pepine, C. Noel Bairey MerzBackgroundA significant number of women with signs and symptoms of ischemia with no obstructive coronary artery disease (INOCA) have coronary vascular dysfunction, detected by invasive coronary reactivity testing (CRT). However, the no...
Source: American Heart Journal - Category: Cardiology Source Type: research
AbstractHyperpolarization is an emerging method in magnetic resonance imaging that allows nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six orders of magnitude at clinically relevant field strengths and administered at high concentration to a subject at the time of measurement. This transient gain in signal has enabled the non-invasive detection and imaging of gas ventilation and diffusion in the lungs, perfusion in blood vessels and tissues, and metabolic conversion in cells, animals, and patients. The rapid development of this  method is based on advances in polarizer tech...
Source: Magnetic Resonance Materials in Physics, Biology and Medicine - Category: Materials Science Source Type: research
Abstract Hyperpolarization is an emerging method in magnetic resonance imaging that allows nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six orders of magnitude at clinically relevant field strengths and administered at high concentration to a subject at the time of measurement. This transient gain in signal has enabled the non-invasive detection and imaging of gas ventilation and diffusion in the lungs, perfusion in blood vessels and tissues, and metabolic conversion in cells, animals, and patients. The rapid development of this method is based on advances in polar...
Source: Magma - Category: Radiology Authors: Tags: MAGMA Source Type: research
We report a 75-year-old woman referred for non-ST-elevation myocardial infarction due to prominent Thebesian veins who displayed a perfusion defect in cardiac magnetic resonance imaging.
Source: Journal of Cardiology Cases - Category: Cardiology Source Type: research
This article is to review recent technical developments and their clinical applications in cancer imaging quantitative measurement of cellular and vascular properties of the tumors.Recent FindingsRapid development of fast magnetic resonance imaging (MRI) technologies over the last decade brought new opportunities in quantitative MRI methods to measure both cellular and vascular properties of tumors simultaneously.SummaryDiffusion MRI (dMRI) and dynamic contrast-enhanced (DCE)-MRI have become widely used to assess the tissue structural and vascular properties, respectively. However, the ultimate potential of these advanced ...
Source: Current Pathobiology Reports - Category: Laboratory Medicine Source Type: research
Publication date: August 2019Source: Revista Portuguesa de Cardiologia (English Edition), Volume 38, Issue 8Author(s): Beatriz Saldanha Santos, Maria João FerreiraAbstractNon-invasive assessment of ischemic heart disease remains a challenging task, even with a large armory of diagnostic modalities. Positron emission tomography (PET) is an advanced radionuclide technique that has been available for decades. Originally used as a research tool that contributed to advances in the understanding of cardiovascular pathophysiology, it is now becoming established in clinical practice and is increasingly used in the diagnosis...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
Introduction: Chronic atherosclerotic mesenteric ischaemia (CMI) is a serious and increasingly common disorder. The gut has a highly collateralised arterial system and it is often difficult to confidently ascribe abdominal symptoms to chronic ischaemia. Whilst detailed anatomical imaging of the mesenteric arteries is straightforward, there is no proven and reliable functional test of mesenteric perfusion. 4D flow magnetic resonance imaging (MR) holds promise in this regard. The aim of this study was to test the feasibility of this technique.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Source Type: research
Abstract Numerous recent technological advances offer the potential to substantially enhance the MRI evaluation of moyamoya disease (MMD). These include high-resolution volumetric imaging, high-resolution vessel wall characterization, improved cerebral angiographic and perfusion techniques, high-field imaging, fast scanning methods, and artificial intelligence. This review discusses the current state-of-the-art MRI applications in these realms, emphasizing key imaging findings, clinical utility, and areas that will benefit from further investigation. Although these techniques may apply to imaging of a wide array o...
Source: Neurosurgical Focus - Category: Neurosurgery Authors: Tags: Neurosurg Focus Source Type: research
Conditions:   Kidney;   Perfusion Imaging;   Ultrasonography Interventions:   Diagnostic Test: Contrast enhanced ultrasound;   Diagnostic Test: Arterial Spin Labelling -Magnetic Resonance Imaging Sponsor:   University of Nottingham Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSIONS: According to the results of postoperative DW-MRI, retrograde perfusion itself might not increase the incidence of postoperative cerebral embolism in properly selected cardiac surgery patients undergoing routine preoperative CTA examination. PMID: 31776305 [PubMed - as supplied by publisher]
Source: Circulation Journal - Category: Cardiology Authors: Tags: Circ J Source Type: research
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