Immunophenotypic Analysis of CAR-T Cells.

Immunophenotypic Analysis of CAR-T Cells. Methods Mol Biol. 2020;2086:195-201 Authors: de Azevedo JTC, Mizukami A, Moço PD, Malmegrim KCR Abstract CAR-T cell immunotherapy is a promising therapeutic modality for cancer patients. The success of CAR-T cell therapy has been associated with the phenotype, activation and functional profiling of infused CAR-T cells. Therefore, immunophenotypic characterization of CAR-T cells during bioprocess is crucial for cell quality control and ultimately for improved antitumor efficacy. In this chapter, we propose a flow cytometry panel to characterize the immunophenotype of the CAR-T subsets. PMID: 31707677 [PubMed - in process]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research

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Source: Hematology ASH Education Program - Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research
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Source: Advances in Anatomic Pathology - Category: Pathology Tags: Review Articles Source Type: research
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Source: Advances in Anatomic Pathology - Category: Pathology Tags: Review Articles Source Type: research
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Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
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Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
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