Oral variant of acantholytic squamous cell carcinoma-Histochemical and immunohistochemical features.

In conclusion, ASCC is an uncommon variant of squamous cell carcinoma. The acantholytic process appears to involve reduced expression of molecular components of both adherens junctions and tight junctions. These findings could suggest a relation to the epithelial mesenchymal transition process and therefore further studies are needed in order to establish such a link and the subsequent possible impact on the clinical outcome of the patients. PMID: 31706621 [PubMed - as supplied by publisher]
Source: Acta Histochemica - Category: Biochemistry Authors: Tags: Acta Histochem Source Type: research