Chemical constituents, experimental and clinical pharmacology of Rosa damascena: a literature review

AbstractContextRosa damascena Mill. is prescribed for the management of chest and abdominal pain, constipation, digestive disorders, menstrual bleeding and liver ailments.ObjectiveThe current review compiles up to date and complete information of whole plant ofR.  damascena with particular emphasis on its numerous scientifically proved pharmacological effects, traditional and folk medicinal uses.Key findingThe data on the pharmacological effects ofR.  damascena were collected from various databases such as PubMed, Wiley Online Library, Elsevier and Web of Science using the keywords like phytoconstituents, pharmacology, medicinal uses and biological activity ofR.  damascene.Rosa damascena has a wide spectrum of bio ‐pharmacological activity like antidepressant, hypoglycaemic, anti‐inflammatory, analgesic, antioxidant and antimicrobial. The main ingredients ofR.  damascena essential oil responsible for pharmacological activity are geraniol and citronellol. Its uses have been widely accepted in traditional system of medicines for the management of numerous diseases of human beings in different dosage forms.SummaryRosa damascena has a significant place in traditional system of medicine. It is cost ‐effective and an important plant with curative application in contemporary medicine. Further studies on the characterization of chemical constituents and scientific basis of pharmacological activity ofR.  damascena should be carried out to evaluate its im...
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research

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