Electronic textiles based wearable electrotherapy for pain relief

Publication date: Available online 10 November 2019Source: Sensors and Actuators A: PhysicalAuthor(s): Meijing Liu, Tyler Ward, Dan Young, Helga Matos, Yang Wei, Jo Adams, Kai YangAbstractElectrotherapy is a common therapeutic treatment used to provide pain relief. The device delivers a mild level of current via electrodes positioned on the skin to interfere with the pain signal and stimulate the release of the body’s own natural painkiller to reduce the pain. This paper presents the materials and fabrication methods used to manufacture a textile based wearable electronic textile (e-textile) with electrodes embedded for joint pain relief. The electrode is made by three functional layers including textile layer, conductive layer, and electrode layer. An electronic control has been developed to deliver interferential therapy. The e-sleeve has been designed and developed alongside patient and public input and tested on six volunteers with self-reported knee joint pain. Four out of six volunteers reported noticeable pain reduction on using the e-textile. The wearable e-textile demonstrated no adverse effects and pilot evidence suggests this has the potential to be a comfortable and easy to use solution for pain relief for people living with osteoarthritis knee joint pain.Graphical abstractElectrotherapy device
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research

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This article reviews the potential role of exosomes in OA regenerative medicine. Special attention is given to mesenchymal stem cells-derived exosomes due to the extensive research on their cartilage repair property and their function as miRNA cargo. More investigations are needed for the effects of exosomes from synovial fluid and chondrocytes in joints. A better understanding of the mechanisms will contribute to a novel and promising therapy for OA patients.
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research
Condition:   Management of Knee Osteoarthritis Pain Interventions:   Drug: Intra articular injection Group;   Device: Radiofrequency Group Sponsors:   Cairo University;   Tanta University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Journal of Back and Musculoskeletal Rehabilitation - Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research
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Source: BMC Family Practice - Category: Primary Care Authors: Tags: Research article Source Type: research
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Source: Clinics in Orthopedic Surgery - Category: Orthopaedics Tags: Clin Orthop Surg Source Type: research
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Source: Journal of Musculoskeletal Neuronal Interactions - Category: Neurology Tags: J Musculoskelet Neuronal Interact Source Type: research
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Source: Journal of Experimental Orthopaedics - Category: Orthopaedics Authors: Tags: Review Source Type: research
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Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: FULL LENGTH Source Type: research
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Source: Journal of Rheumatology - Category: Rheumatology Tags: J Rheumatol Source Type: research
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Source: Trials - Category: Research Source Type: clinical trials
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