Hepatitis B viremia in HIV-coinfected individuals under antiretroviral therapy

ConclusionsDespite being on ART, a significant proportion of HIV/HBV-coinfected individuals present HBV viremia. Characterization of factors that are associated with this finding may help professionals provide better management to these patients.
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research

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Purpose of review Subcutaneous implants are a promising technology to enable long-acting parenteral delivery of antiretroviral drugs (ARV) because they may be able to provide protective drugs concentrations for a year or longer following a single implant. The present review covers the current status of preclinical and clinical development of antiretroviral implants. Recent findings Over the past three decades, subcutaneous implants have been widely used for long-acting hormonal contraception and the treatment of hormonally-driven malignancies. They are economical and scalable to manufacture, but require special proced...
Source: Current Opinion in HIV and AIDS - Category: Infectious Diseases Tags: LONG ACTING ART FOR TREATMENT AND PREVENTION: Edited by Martin Markowitz Source Type: research
Abstract Background and objectives: In Romania, the human immunodeficiency virus (HIV) epidemic is almost the same as it is in Central Europe, with some differences; particularity the following one: people with nosocomial HIV infection, also known as Romanian cohort. Aim: The study aimed to present a local view of HIV infection in the North-West part of Romania, and to identify the particularities of patients under medical care in the Cluj AIDS Center. Materials and Methods: The demographic characteristics (age and gender), and medical and epidemiological data (stage of HIV infection and mode of transmission) of p...
Source: Medicina (Kaunas) - Category: Universities & Medical Training Authors: Tags: Medicina (Kaunas) Source Type: research
By Margarite Nathe, Principal Editor/Writer, IntraHealth International ; Lucy Mphuru, Country Director&Project Director, Tohara Plus Project Lucy Mphuru (center left) talks with health workers and clients at an IntraHealth-supported mobile clinic in Shinyanga that provides voluntary male circumcision services. Photo by Trevor Snapp for IntraHealth International.November 26, 2019Lucy Mphuru has a big job.Every day, she and her team at IntraHealth International in Tanzania work with frontline health workers and government partners to improve health services in a country of 58 million—1.6 million of whom live ...
Source: IntraHealth International - Category: International Medicine & Public Health Authors: Tags: HIV & AIDS Community Engagement Leadership and Governance World AIDS Day Health Workforce Systems Source Type: news
Conclusion: Prevalence of transfusion-transmissible viral infections was higher among hemodialysis patients, especially HCV infection which was an alarming situation and therefore strict adherence to infection control strategies, barrier precautions, and preventive measures, including routine hepatitis B vaccination and regular virological follow-up were recommended along with regular education and training programs of technical and nursing personnel's involved with dialysis patients.
Source: Indian Journal of Sexually Transmitted Diseases - Category: Infectious Diseases Authors: Source Type: research
Background: Global increase of people infected with HIV (PIH) is causing changes in tuberculosis (TB) clinical and epidemiological data. HIV infection increases up to 20 times the chance of progression from latent infection to active forms of TB.Purpose: The paper aims to assess patients with TB-HIV coinfection in Olt county of Romania registered in Regional Center for Monitoring and Evaluation of HIV/AIDS of Craiova (demographics, symptoms, immunologic evaluation, TB type, TB related number of treatments) in order to identify risk factors for progression to active TB in this subset of patients.Material and Method: We perf...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
We previously reported that four doses or four double doses of hepatitis B vaccination regimens could not significantly increase a response rate compared with standard doses. However, the antibody levels were ...
Source: AIDS Research and Therapy - Category: Infectious Diseases Authors: Tags: Short Report Source Type: research
CONCLUSIONS: Despite the highly effectiveness of the standard hepatitis B vaccination regimen at 6 months after completion, the long-term immunogenicity was lower than the four double doses regimen among HIV-infected adults with CD4+ cell counts > 200 cells/mm3 and undetectable plasma HIV-1 RNA. The standard vaccination regimen may not be the best strategy to provide long-term immune response against hepatitis B virus among HIV-infected individuals. Trial registration NCT1289106, NCT02713620. PMID: 31711528 [PubMed - in process]
Source: AIDS Research and Therapy - Category: Infectious Diseases Authors: Tags: AIDS Res Ther Source Type: research
CONCLUSIONS: Despite being on ART, a significant proportion of HIV/HBV-coinfected individuals present HBV viremia. Characterization of factors that are associated with this finding may help professionals provide better management to these patients. PMID: 31715124 [PubMed - as supplied by publisher]
Source: Braz J Infect Dis - Category: Infectious Diseases Authors: Tags: Braz J Infect Dis Source Type: research
Following substantial investments in national blood transfusion service laboratories, in 2017 investigators tested proficiency at 84 blood center laboratories in seven African countries.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Blood Safety Blood supply safety Global HIV/AIDS Hepatitis B Screening Hepatitis C MMWR Morbidity & Mortality Weekly Report South Africa Source Type: news
Abstract Hepatitis B surface antigen (HBsAg) level plays an important role in conjunction with other markers such as hepatitis B envelope antigen (HBeAg) and hepatitis B virus (HBV) deoxyribonucleic acid levels to predict disease activity in chronic Hepatitis B (CHB). Quantification of HBsAg is useful in differentiating carriers from active hepatitis in HBeAg negative patients, and current guidelines ecommend monitoring of pegylated interferon alpha treatment in CHB infection. However, there are only few studies about the role of quantitative HBsAg (qHBsAg) monitoring in HIV-HBV coinfected patients. Studies have s...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
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