Bimodal Right Ventricular Dysfunction After Postnatal Hyperoxia Exposure: Implications for the Preterm Heart.

CONCLUSION: There appears to be a "honeymoon period" where cardiac hemodynamic and mitochondrial function normalizes following postnatal hyperoxia exposure, only to decline again with ongoing aging. This finding may have significant implications if a long-term pulmonary vascular screening program were to be developed for children or adults with a history of severe prematurity. Further investigation into the mechanisms of recovery are warranted.
PMID: 31702968 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Heart and Circulatory Physiology - November 7, 2019 Category: Physiology Authors: Kumari S, Braun RK, Tetri L, Barton GP, Hacker TA, Goss KN Tags: Am J Physiol Heart Circ Physiol Source Type: research