Chromosomal Abnormalities Common in Couples With Recurrent Miscarriage Chromosomal Abnormalities Common in Couples With Recurrent Miscarriage

Almost 12% of couples with recurrent miscarriage have chromosomal abnormalities, according to results of low-pass genome sequencing (GS) studies.Reuters Health Information
Source: Medscape Pathology Headlines - Category: Pathology Tags: Ob/Gyn & Women ' s Health News Source Type: news

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Publication date: Available online 14 November 2019Source: Reproductive BioMedicine OnlineAuthor(s): Zhiqin Bu, Linli Hu, Yingchun Su, Yihong Guo, Jun Zhai, Yingpu SunAbstractResearch questionThe aim was to investigate factors related to early spontaneous miscarriage during in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI) treatment.DesignA total of 21,485 clinical pregnancy cycles were included in the analysis. First, early spontaneous miscarriage rates were compared among different groups according to female age, body mass index (BMI), number of previous miscarriages, etc. Then, the spontaneous miscar...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
ConclusionsOur findings confirm previous results of safety in maternal and fetal outcomes in CAB-induced pregnancies; nevertheless, CAB maintenance after pregnancy confirmation was associated with higher miscarriage rate; result that must be further confirmed.
Source: Pituitary - Category: Endocrinology Source Type: research
Since the introduction of the Hostile Environment, hospitals have had to charge undocumented migrants living in the UK for non-emergency medical care. This includes pregnant women. Bills of £7,000 for the basic maternity package (an uncomplicated pregnancy and delivery) are the norm. Often they are much higher. One of the more shocking cases Doctors of the World supported was a woman sent a bill of £9,600 soon after her 22 week miscarriage. A pregnancy is a great undertaking for all women. But time and time again we see pregnant women at the clinic who delay accessing or avoid visiting hospitals altogether for...
Source: Doctors of the World News - Category: International Medicine & Public Health Authors: Tags: Uncategorised Source Type: news
ConclusionLaparoscopic surgery is a feasible option for tubal stump pregnancy, associated with favorable pregnancy outcomes.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Conclusion.Planned pregnancy might be pragmatic in female patients with CML on TKIs. Achieving deep molecular response and, importantly, MMR duration ≥3.5 years were significantly associated with maintaining MMR during pregnancy.Implications for Practice.Female patients with chronic myeloid leukemia on tyrosine kinase inhibitors (TKIs) wishing to conceive are currently advised to discontinue TKIs before conception. However, the ideal degree and duration of response before stopping TKI, in addition to whether there will be any adverse effect caused by a short exposure of TKI, is unknown. Data of 17 female patients, who a...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Leukemias, Hematologic Malignancies Source Type: research
ConclusionsOur method achieved accurate detection of triploidy in the miscarriage tissue and has the potential to detect more chromosomal abnormality types such as uniparental disomy (UPD) using a single LC-WGS approach.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
ConclusionObesity is closely associated with primary infertility and PCOD. Menstrual abnormalities associated with PCOD significantly improve after bariatric surgery with significant improvement in fertility along with maternal outcomes.
Source: Obesity Surgery - Category: Surgery Source Type: research
The aim of this retrospective analysis is to explore whether growth hormone (GH) pretreatment is beneficial for patients with poor ovarian reserve undertaking in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment. Poor ovarian reserve patients with anti-Mullerian hormone (AMH)
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
The role of growth hormone (GH) in human fertility is widely debated with some studies demonstrating improvements in oocyte yield, enhanced embryo quality, and in some cases increased live births with concomitant decreases in miscarriage rates. However, the basic biological mechanisms leading to these clinical differences are not well-understood. GH and the closely-related insulin-like growth factor (IGF) promote body growth and development via action on key metabolic organs including the liver, skeletal muscle, and bone. In addition, their expression and that of their complementary receptors have also been detected in var...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
m Ekmekcioglu Birth related complications and comorbidities are highly associated with a poor nutritional status of pregnant women, whereas iron and iodine are among especially important trace elements for healthy maternal and fetal outcomes. The study compares the status of iron, iodine, and related functional parameters in pregnant and non-pregnant women from a developing country and associates the data with pregnancy complications. The concentrations of ferritin, hemoglobin (Hb), total triiodothyronine (TT3), total thyroxine (TT4), and thyroid-stimulating hormone (TSH) were determined in the blood serum of 80 pregna...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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