A single injection of vitamin D3 improves insulin sensitivity and beta cell function but not muscle damage or the inflammatory and cardiovascular responses to an acute bout of resistance exercise in vitamin-D deficient resistance-trained males.

A single injection of vitamin D3 improves insulin sensitivity and beta cell function but not muscle damage or the inflammatory and cardiovascular responses to an acute bout of resistance exercise in vitamin-D deficient resistance-trained males. Br J Nutr. 2019 Nov 08;:1-21 Authors: Larky DA, Kheirollah A, Bagheri R, Ghaffari MA, Mard SA, Hashemi SJ, Mir I, Wong A Abstract Vitamin-D deficiency is now recognized problem affecting multiple physiological functions. The aim of this study was to evaluate the effect of a single dose of vitamin D3injection on the inflammatory, muscular damage, metabolic and cardiovascular responses to an acute bout of resistance exercise (RE)in vitamin D-deficient resistance-trained males.Blood samples from 14 vitamin D-deficient resistance-trained males were obtained during two separate trials: lower vitamin-D (LVD) and higher vitamin-D (HVD, after vitamin D3injection). Metabolic, inflammatory, muscle damage and cardiovascular markers were evaluated at baseline, immediately and 1-hour after RE. There were significant trial-by-time interactions for insulin and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR) which significantly (P ˂ 0.05) declined for 1-hour after RE in the HVD compared to LVD trial. Homeostasis Model Assessment of β-Cell Function (HOMA-ß) decline at 1-hour post-RE in the HVD trial. There was also a time-effect for blood sugar which significantly (P ˂ 0.05) decreased and for ...
Source: The British Journal of Nutrition - Category: Nutrition Authors: Tags: Br J Nutr Source Type: research